C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytokine inducible SH2-containing protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000114737 CISH 9606 - 3:50606490-50611831 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000348721 CISH-001 50606522-50611831 protein_coding
  ENST00000443053 CISH-002 50606496-50611772 protein_coding
  ENST00000491847 CISH-003 50606490-50611761 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENST00000348721ENST00000443053ENST00000491847
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000348721 16.558±0.00 7.384±0.00 2.097±0.00 1.692±0.00 3.638±1.86 2.468±0.62 15.760±13.29 11.350±10.52 15.452±13.50 8.823±5.93 10.350±7.22 16.927±6.12 3.929±0.00
ENST00000443053 N/A N/A N/A N/A N/A N/A 2.502±0.00 N/A N/A N/A N/A N/A N/A
ENST00000491847 N/A N/A 0.845±0.00 N/A N/A 0.381±0.00 0.880±0.00 N/A 0.978±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008D8 CIL_0008D8_0001 VISTA 3:50299047-50902727

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 NAS regulation of cell growth
GO:0003674 ND molecular_function
GO:0005515 IPI protein binding
GO:0005575 ND cellular_component
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0007205 IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0009968 IEA negative regulation of signal transduction
GO:0016567 IEA protein ubiquitination
GO:0035556 NAS:IEA intracellular signal transduction
GO:0060397 TAS JAK-STAT cascade involved in growth hormone signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016773 cishb cytokine inducible SH2-containing protein b protein_coding Danio_rerio
ENSDARG00000060316 cish cytokine inducible SH2-containing protein protein_coding Danio_rerio
ENSMUSG00000032578 Cish cytokine inducible SH2-containing protein protein_coding Mus_musculus

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