C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: STEAP family member 3, metalloreductase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115107 STEAP3 9606 + 2:119223831-119265652 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000393106 STEAP3-002 119223831-119265652 protein_coding
  ENST00000393107 STEAP3-004 119223853-119263698 protein_coding
  ENST00000393110 STEAP3-001 119223831-119265652 protein_coding
  ENST00000409811 STEAP3-003 119223853-119263698 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000393106ENST00000393107ENST00000393110
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000393106 5.212±0.00 5.244±0.00 N/A 2.876±0.00 9.590±0.00 1.834±0.00 4.303±0.00 6.595±0.17 N/A 3.719±0.00 10.636±0.00 5.666±3.85 4.099±2.53 1.280±0.98
ENST00000393107 N/A N/A N/A N/A N/A N/A 0.252±0.00 N/A N/A N/A N/A 1.529±0.00 N/A N/A
ENST00000393110 N/A N/A 0.341±0.00 0.266±0.00 N/A 0.448±0.00 0.955±0.87 4.829±3.69 5.529±4.70 1.785±0.00 1.085±0.00 1.640±0.00 1.700±0.10 0.106±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00093M CIL_00093M_0001 VISTA 2:119187057-119791464
CIL_0002WQ CIL_0002WQ_0002 CGP 2:119223831-119366828

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000293 IEA ferric-chelate reductase activity
GO:0005515 IPI protein binding
GO:0005768 IEA endosome
GO:0005771 IDA multivesicular body
GO:0005886 IEA plasma membrane
GO:0006826 IEA iron ion transport
GO:0006879 TAS cellular iron ion homeostasis
GO:0006915 IEA apoptotic process
GO:0007049 IEA cell cycle
GO:0008823 IEA cupric reductase activity
GO:0009306 IDA protein secretion
GO:0010008 TAS endosome membrane
GO:0015677 IEA copper ion import
GO:0016021 IEA integral component of membrane
GO:0033572 TAS transferrin transport
GO:0043065 IEA positive regulation of apoptotic process
GO:0046872 IEA metal ion binding
GO:0052851 IEA ferric-chelate reductase (NADPH) activity
GO:0055085 TAS transmembrane transport
GO:0055114 IEA oxidation-reduction process
GO:0097461 IEA ferric iron import into cell
GO:1902167 IEA positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:1990182 IEA exosomal secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075641 steap3 STEAP family member 3, metalloreductase protein_coding Danio_rerio
ENSMUSG00000026389 Steap3 STEAP family member 3 protein_coding Mus_musculus

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