C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: acyl-CoA dehydrogenase, long chain
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115361 ACADL 9606 - 2:210187939-210225491 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000233710 ACADL-001 210187939-210225491 protein_coding
  ENST00000482502 ACADL-004 210209589-210216719 retained_intron
  ENST00000482523 ACADL-003 210218065-210224849 retained_intron
  ENST00000498120 ACADL-002 210217475-210225447 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000233710ENST00000482502ENST00000482523ENST00000498120
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000233710 1.374±0.00 0.211±0.00 N/A 0.300±0.23 3.816±0.00 0.463±0.01 0.165±0.12 4.186±0.00 2.502±0.00 1.564±0.26 0.933±0.21 1.102±1.12 0.898±0.47 1.240±0.73
ENST00000482502 N/A N/A 1.041±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.167±0.00 N/A N/A
ENST00000482523 N/A N/A N/A N/A 0.294±0.00 N/A N/A 3.741±0.00 N/A N/A N/A N/A N/A N/A
ENST00000498120 N/A 0.124±0.00 N/A N/A N/A N/A N/A N/A 0.322±0.00 4.219±0.00 N/A 0.676±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002J3 CIL_0002J3_0001 CGP 2:210021423-210225491

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000062 IEA fatty-acyl-CoA binding
GO:0001659 ISS temperature homeostasis
GO:0003995 TAS:IEA acyl-CoA dehydrogenase activity
GO:0004466 ISS long-chain-acyl-CoA dehydrogenase activity
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0006635 TAS fatty acid beta-oxidation
GO:0008152 IEA metabolic process
GO:0016401 ISS palmitoyl-CoA oxidase activity
GO:0016627 IEA oxidoreductase activity, acting on the CH-CH group of donors
GO:0019254 ISS carnitine metabolic process, CoA-linked
GO:0031966 IEA mitochondrial membrane
GO:0033539 ISS fatty acid beta-oxidation using acyl-CoA dehydrogenase
GO:0042413 ISS carnitine catabolic process
GO:0042758 IEA long-chain fatty acid catabolic process
GO:0044242 ISS cellular lipid catabolic process
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045717 ISS negative regulation of fatty acid biosynthetic process
GO:0046322 ISS negative regulation of fatty acid oxidation
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0051289 IEA protein homotetramerization
GO:0055114 ISS:IEA oxidation-reduction process
GO:0090181 ISS regulation of cholesterol metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088357 acadl acyl-Coenzyme A dehydrogenase, long chain protein_coding Danio_rerio
ENSMUSG00000026003 Acadl acyl-Coenzyme A dehydrogenase, long-chain protein_coding Mus_musculus

Loading