C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: insulin-like growth factor binding protein 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115461 IGFBP5 9606 - 2:216672105-216695525 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000233813 IGFBP5-001 216672105-216695525 protein_coding
  ENST00000449583 IGFBP5-003 216678853-216694794 protein_coding
  ENST00000486341 IGFBP5-004 216678758-216694667 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000233813
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000233813 306.482±0.00 156.451±0.00 12.639±0.00 19.980±17.33 68.867±49.02 84.440±66.69 23.341±19.13 60.949±57.23 16.302±0.33 27.378±18.71 27.145±20.15 256.925±245.27 151.877±54.54 111.482±99.18

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000AM CIL_0000AM_0002 CGP 2:216632828-216695525
CIL_0005MA CIL_0005MA_0001 CGP 2:216672105-216860064

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 IEA regulation of cell growth
GO:0001649 IEA osteoblast differentiation
GO:0001968 IEA fibronectin binding
GO:0005515 IPI protein binding
GO:0005520 IEA insulin-like growth factor binding
GO:0005576 NAS:IEA extracellular region
GO:0006006 IEA glucose metabolic process
GO:0007165 NAS signal transduction
GO:0010906 IEA regulation of glucose metabolic process
GO:0014912 IDA negative regulation of smooth muscle cell migration
GO:0016942 IC insulin-like growth factor binding protein complex
GO:0017148 IDA negative regulation of translation
GO:0030336 IDA negative regulation of cell migration
GO:0031069 IEA hair follicle morphogenesis
GO:0031994 IPI insulin-like growth factor I binding
GO:0035556 IEA intracellular signal transduction
GO:0040008 IEA regulation of growth
GO:0042593 IEA glucose homeostasis
GO:0043568 IEA positive regulation of insulin-like growth factor receptor signaling pathway
GO:0043569 IDA negative regulation of insulin-like growth factor receptor signaling pathway
GO:0044267 TAS cellular protein metabolic process
GO:0044342 IEA type B pancreatic cell proliferation
GO:0045668 IEA negative regulation of osteoblast differentiation
GO:0048630 IEA skeletal muscle tissue growth
GO:0048662 IDA negative regulation of smooth muscle cell proliferation
GO:0051146 IEA striated muscle cell differentiation
GO:0051897 IEA positive regulation of protein kinase B signaling
GO:0060056 IEA mammary gland involution
GO:0071320 IDA cellular response to cAMP
GO:0071407 IDA cellular response to organic cyclic compound

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025348 igfbp5b insulin-like growth factor binding protein 5b protein_coding Danio_rerio
ENSDARG00000039264 igfbp5a insulin-like growth factor binding protein 5a protein_coding Danio_rerio
ENSMUSG00000026185 Igfbp5 insulin-like growth factor binding protein 5 protein_coding Mus_musculus

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