C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 1 receptor, type I
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115594 IL1R1 9606 + 2:102064544-102179874 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000409288 IL1R1-002 102142786-102175759 protein_coding
  ENST00000409329 IL1R1-004 102104569-102175817 protein_coding
  ENST00000409589 IL1R1-005 102104563-102179866 protein_coding
  ENST00000409929 IL1R1-006 102070376-102176759 protein_coding
  ENST00000410023 IL1R1-001 102142786-102179874 protein_coding
  ENST00000413623 IL1R1-008 102153949-102176842 nonsense_mediated_decay
  ENST00000422532 IL1R1-009 102164774-102171829 nonsense_mediated_decay
  ENST00000424272 IL1R1-013 102070376-102176759 protein_coding
  ENST00000428279 IL1R1-003 102141819-102176377 protein_coding
  ENST00000430171 IL1R1-007 102153963-102166173 protein_coding
  ENST00000442590 IL1R1-010 102142306-102165162 protein_coding
  ENST00000450319 IL1R1-011 102141771-102165136 protein_coding
  ENST00000452403 IL1R1-012 102064544-102164953 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000409329ENST00000409589ENST00000410023ENST00000424272
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000409329 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.327±0.00 N/A N/A
ENST00000409589 N/A N/A N/A N/A N/A N/A N/A N/A 3.863±0.00 N/A N/A N/A 35.971±0.00 N/A
ENST00000410023 30.510±0.00 9.382±0.00 0.973±0.00 0.542±0.50 9.840±3.84 13.623±11.36 6.875±0.00 8.345±0.00 3.313±1.47 24.821±19.92 4.348±0.00 12.451±6.58 29.962±14.86 13.319±0.00
ENST00000424272 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.206±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004QZ CIL_0004QZ_0001 CGP 2:101991844-102179874
CIL_0004QY CIL_0004QY_0001 CGP 2:102064544-102240002

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002020 IEA protease binding
GO:0004871 TAS signal transducer activity
GO:0004888 TAS transmembrane signaling receptor activity
GO:0004908 IDA interleukin-1 receptor activity
GO:0004909 IEA interleukin-1, Type I, activating receptor activity
GO:0005161 IPI platelet-derived growth factor receptor binding
GO:0005515 IEA protein binding
GO:0005576 IEA extracellular region
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006955 TAS immune response
GO:0007165 IEA signal transduction
GO:0007166 TAS cell surface receptor signaling pathway
GO:0009986 IEA cell surface
GO:0016020 IDA membrane
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0050727 IEA regulation of inflammatory response
GO:0070498 IEA interleukin-1-mediated signaling pathway
GO:0070555 IDA response to interleukin-1

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090844 IL1R1 interleukin 1 receptor, type I protein_coding Danio_rerio
ENSMUSG00000026072 Il1r1 interleukin 1 receptor, type I protein_coding Mus_musculus

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