C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 18 receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115604 IL18R1 9606 + 2:102311529-102398775 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000233957 IL18R1-201 102356283-102398775 protein_coding
  ENST00000334376 IL18R1-202 102362637-102373981 protein_coding
  ENST00000409599 IL18R1-001 102355929-102398758 protein_coding
  ENST00000410040 IL18R1-003 102311529-102396886 protein_coding
  ENST00000466357 IL18R1-004 102356045-102362916 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENST00000233957ENST00000409599ENST00000410040
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENST00000233957 N/A N/A N/A 1.201±0.00 N/A N/A 0.916±0.00 N/A 8.946±0.00 0.290±0.00 0.552±0.30 0.251±0.00
ENST00000409599 6.619±0.00 1.194±0.00 N/A 0.250±0.00 0.846±0.59 0.691±0.00 N/A 1.696±1.07 10.938±0.00 0.296±0.00 N/A 0.646±0.00
ENST00000410040 N/A N/A 0.080±0.00 0.296±0.00 0.717±0.00 N/A 1.576±0.00 N/A 15.225±0.00 0.199±0.00 0.518±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004R1 CIL_0004R1_0001 CGP 2:102186973-102352037
CIL_0004R0 CIL_0004R0_0001 CGP 2:102311502-102398775
CIL_0004R3 CIL_0004R3_0001 CGP 2:102311529-102452565

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004872 TAS receptor activity
GO:0004908 IEA interleukin-1 receptor activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006955 TAS immune response
GO:0007165 TAS:IEA signal transduction
GO:0016021 IEA integral component of membrane
GO:0030101 IEA natural killer cell activation
GO:0032729 IEA positive regulation of interferon-gamma production
GO:0035655 IEA interleukin-18-mediated signaling pathway
GO:0042008 IEA interleukin-18 receptor activity
GO:0042346 IEA positive regulation of NF-kappaB import into nucleus
GO:0045063 IEA T-helper 1 cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000026070 Il18r1 interleukin 18 receptor 1 protein_coding Mus_musculus

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