C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pappalysin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000116183 PAPPA2 9606 + 1:176463171-176845605 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000367661 PAPPA2-002 176463171-176691204 protein_coding
  ENST00000367662 PAPPA2-001 176463171-176845605 protein_coding
  ENST00000479836 PAPPA2-005 176791445-176836802 processed_transcript
  ENST00000486075 PAPPA2-004 176553488-176555736 processed_transcript
  ENST00000493665 PAPPA2-003 176537303-176555711 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000367661ENST00000367662ENST00000486075ENST00000493665
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000367661 N/A N/A N/A N/A 0.044±0.00 N/A N/A N/A N/A 0.017±0.00 N/A N/A
ENST00000367662 1.383±0.00 0.228±0.00 0.020±0.00 0.105±0.00 0.068±0.00 1.056±1.04 0.211±0.09 0.030±0.01 0.001±0.00 0.038±0.01 47.909±50.00 0.365±0.09
ENST00000486075 N/A N/A 0.263±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000493665 N/A N/A N/A 1.288±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 NAS regulation of cell growth
GO:0005515 IEA protein binding
GO:0005576 TAS extracellular region
GO:0005622 NAS intracellular
GO:0006508 IDA proteolysis
GO:0008237 IDA metallopeptidase activity
GO:0008270 NAS zinc ion binding
GO:0016020 IEA membrane
GO:0030154 IEA cell differentiation
GO:0044267 TAS cellular protein metabolic process
GO:0060349 IEA bone morphogenesis
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076020 pappa2 pappalysin 2 protein_coding Danio_rerio
ENSMUSG00000073530 Pappa2 pappalysin 2 protein_coding Mus_musculus

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