C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transmembrane protein 59
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000116209 TMEM59 9606 - 1:54031663-54053504 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000234831 TMEM59-001 54031676-54053438 protein_coding
  ENST00000371337 TMEM59-004 54045486-54053192 protein_coding
  ENST00000371341 TMEM59-005 54031966-54053504 protein_coding
  ENST00000371344 TMEM59-003 54031676-54044942 protein_coding
  ENST00000371348 TMEM59-002 54031663-54048013 protein_coding
  ENST00000420738 TMEM59-007 54036599-54053412 protein_coding
  ENST00000440019 TMEM59-006 54036599-54053441 protein_coding
  ENST00000452421 TMEM59-008 54036602-54053405 protein_coding
  ENST00000470395 TMEM59-009 54032019-54036802 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000234831ENST00000371341ENST00000440019ENST00000470395
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000234831 74.824±0.00 67.031±0.00 19.355±0.00 60.010±24.18 73.933±36.71 88.953±38.47 31.942±20.14 83.216±28.73 46.887±17.73 64.996±28.53 16.812±11.59 53.146±21.81 105.335±22.88 74.067±42.88
ENST00000371341 N/A 24.196±0.00 N/A N/A N/A N/A 10.335±7.75 N/A 24.241±0.00 25.345±0.00 9.305±7.31 N/A N/A 21.306±0.00
ENST00000440019 N/A N/A N/A N/A N/A N/A 27.063±0.00 N/A 30.349±0.00 65.572±0.00 N/A 49.655±0.00 72.796±9.91 N/A
ENST00000470395 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.898±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000137 IDA Golgi cis cisterna
GO:0000138 IDA Golgi trans cisterna
GO:0004175 IEA endopeptidase activity
GO:0004867 IEA serine-type endopeptidase inhibitor activity
GO:0005515 IPI protein binding
GO:0005764 IDA lysosome
GO:0005770 IDA late endosome
GO:0005797 IDA Golgi medial cisterna
GO:0005886 IEA plasma membrane
GO:0006508 IEA proteolysis
GO:0006914 IEA autophagy
GO:0010508 IMP positive regulation of autophagy
GO:0010955 IDA negative regulation of protein processing
GO:0016021 IEA integral component of membrane
GO:0070062 IDA extracellular vesicular exosome
GO:0090005 IDA negative regulation of establishment of protein localization to plasma membrane
GO:0090285 IDA negative regulation of protein glycosylation in Golgi

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019033 tmem59 transmembrane protein 59 protein_coding Danio_rerio
ENSMUSG00000028618 Tmem59 transmembrane protein 59 protein_coding Mus_musculus

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