C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitochondrial trans-2-enoyl-CoA reductase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000116353 MECR 9606 - 1:29192873-29230942 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263702 MECR-001 29193817-29230932 protein_coding
  ENST00000373791 MECR-002 29192873-29230924 protein_coding
  ENST00000453185 MECR-011 29195944-29206828 processed_transcript
  ENST00000463052 MECR-012 29202017-29230901 processed_transcript
  ENST00000463412 MECR-006 29194032-29216029 nonsense_mediated_decay
  ENST00000464511 MECR-017 29200324-29203170 processed_transcript
  ENST00000464915 MECR-005 29216037-29223549 processed_transcript
  ENST00000473030 MECR-019 29193874-29216613 processed_transcript
  ENST00000474946 MECR-013 29206774-29230915 processed_transcript
  ENST00000475773 MECR-015 29193811-29203201 processed_transcript
  ENST00000475861 MECR-014 29203216-29230897 processed_transcript
  ENST00000478505 MECR-010 29195947-29220912 processed_transcript
  ENST00000482610 MECR-008 29216093-29230891 processed_transcript
  ENST00000483435 MECR-016 29193817-29200589 processed_transcript
  ENST00000484012 MECR-004 29216601-29230942 processed_transcript
  ENST00000489248 MECR-009 29203142-29230906 processed_transcript
  ENST00000490529 MECR-018 29196142-29230894 processed_transcript
  ENST00000493928 MECR-003 29220883-29230942 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263702ENST00000373791ENST00000463412ENST00000464915ENST00000473030ENST00000474946ENST00000475861ENST00000478505ENST00000483435ENST00000490529
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263702 4.584±0.00 4.549±0.00 N/A 6.266±3.90 18.493±16.65 2.528±0.00 3.939±3.50 5.892±2.14 4.320±3.10 2.714±0.00 7.651±0.00 6.744±0.71 10.370±4.57 3.617±0.20
ENST00000373791 1.532±0.00 N/A N/A 2.847±1.15 5.462±0.00 N/A 1.330±0.00 2.041±0.00 N/A 0.642±0.00 0.510±0.00 2.786±0.76 2.825±0.88 N/A
ENST00000463412 N/A N/A N/A N/A N/A N/A N/A N/A 0.775±0.00 1.198±0.00 N/A 0.903±0.00 N/A N/A
ENST00000464915 N/A N/A 0.723±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000473030 3.248±0.00 N/A N/A N/A N/A N/A N/A N/A 2.842±0.00 N/A N/A N/A N/A N/A
ENST00000474946 N/A N/A N/A N/A N/A N/A N/A N/A 1.411±0.00 0.619±0.00 N/A N/A N/A 3.666±0.00
ENST00000475861 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.016±0.00 N/A N/A
ENST00000478505 N/A N/A N/A N/A N/A 1.042±0.00 N/A N/A N/A N/A 1.359±0.00 N/A N/A N/A
ENST00000483435 N/A 6.296±0.00 N/A N/A N/A 2.673±0.31 0.615±0.00 N/A N/A 1.620±0.00 4.718±2.91 6.572±0.00 N/A 3.430±0.00
ENST00000490529 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.524±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005739 IDA mitochondrion
GO:0006631 IDA fatty acid metabolic process
GO:0006633 IEA fatty acid biosynthetic process
GO:0008270 IEA zinc ion binding
GO:0016491 IEA oxidoreductase activity
GO:0016747 IEA transferase activity, transferring acyl groups other than amino-acyl groups
GO:0019166 IDA trans-2-enoyl-CoA reductase (NADPH) activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032326 mecr mitochondrial trans-2-enoyl-CoA reductase protein_coding Danio_rerio
ENSMUSG00000028910 Mecr mitochondrial trans-2-enoyl-CoA reductase protein_coding Mus_musculus

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