C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000116586 LAMTOR2 9606 + 1:156054752-156058510 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000368302 LAMTOR2-003 156054850-156058503 protein_coding
  ENST00000368304 LAMTOR2-002 156054792-156058506 protein_coding
  ENST00000368305 LAMTOR2-001 156054752-156058510 protein_coding
  ENST00000463371 LAMTOR2-006 156055496-156058506 processed_transcript
  ENST00000487106 LAMTOR2-004 156055085-156058506 processed_transcript
  ENST00000489664 LAMTOR2-005 156054821-156055993 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000368302ENST00000368304ENST00000368305ENST00000463371ENST00000487106ENST00000489664
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000368302 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 228.413±0.00 87.146±0.00 35.134±0.00
ENST00000368304 N/A N/A N/A 9.339±0.00 N/A 0.987±0.00 2.320±1.77 N/A 0.983±0.00 N/A 8.371±0.00 N/A N/A N/A
ENST00000368305 29.713±0.00 46.999±0.00 1.871±0.00 13.111±2.14 24.462±21.48 23.253±20.43 9.116±6.22 29.240±15.74 33.043±29.46 18.245±15.84 23.327±16.71 41.498±22.46 47.644±23.47 17.360±6.48
ENST00000463371 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.937±0.00 N/A N/A
ENST00000487106 N/A N/A N/A 3.204±0.00 N/A N/A 0.897±0.00 N/A N/A 0.921±0.00 N/A N/A N/A 4.279±0.00
ENST00000489664 N/A N/A N/A N/A 0.371±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000898 CIL_000898_0001 VISTA 1:155789635-156392759
CIL_0008P5 CIL_0008P5_0001 VISTA 1:155795688-156399252

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000186 IEA activation of MAPKK activity
GO:0005085 IDA guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005765 IDA lysosomal membrane
GO:0005770 ISS late endosome
GO:0016049 IMP cell growth
GO:0032008 IMP positive regulation of TOR signaling
GO:0032947 IDA protein complex scaffold
GO:0034613 IMP cellular protein localization
GO:0043547 IDA positive regulation of GTPase activity
GO:0070062 IDA extracellular vesicular exosome
GO:0071230 IMP cellular response to amino acid stimulus
GO:0071986 IDA Ragulator complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039872 lamtor2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 protein_coding Danio_rerio
ENSMUSG00000028062 Lamtor2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 protein_coding Mus_musculus

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