C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 5-methyltetrahydrofolate-homocysteine methyltransferase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000116984 MTR 9606 + 1:236795281-236903981 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000366576 MTR-002 236835616-236900418 protein_coding
  ENST00000366577 MTR-001 236795310-236903981 protein_coding
  ENST00000463959 MTR-004 236795615-236853088 processed_transcript
  ENST00000470570 MTR-003 236894341-236900409 processed_transcript
  ENST00000535889 MTR-201 236795281-236903981 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000366576ENST00000366577ENST00000463959ENST00000470570ENST00000535889
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000366576 2.949±0.00 2.403±0.00 2.281±0.00 0.796±0.00 2.464±1.22 1.596±0.00 3.090±1.09 1.355±0.00 1.660±1.31 1.930±0.00 1.368±0.00 3.020±0.00 0.910±0.06 3.518±0.00
ENST00000366577 3.420±0.00 1.700±0.00 1.178±0.00 0.863±0.14 2.243±0.50 0.830±0.00 2.553±0.50 1.831±1.64 1.706±0.99 1.138±0.00 1.897±0.93 2.243±1.94 1.752±0.20 2.090±0.95
ENST00000463959 N/A N/A 4.334±0.00 3.642±0.00 5.335±0.00 2.767±0.00 4.138±0.00 N/A 9.099±0.00 N/A 5.872±0.00 3.417±0.00 N/A N/A
ENST00000470570 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.876±0.00 N/A N/A 2.773±0.00
ENST00000535889 2.200±0.00 2.388±0.00 N/A 1.542±0.00 N/A 1.924±0.00 2.644±0.00 1.906±0.00 0.220±0.00 1.514±0.00 1.468±0.00 N/A 1.227±0.00 2.674±0.22

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00097Y CIL_00097Y_0001 VISTA 1:236338883-236940914
CIL_0008IY CIL_0008IY_0001 VISTA 1:236697312-237300217
CIL_0008J9 CIL_0008J9_0001 VISTA 1:236711218-237313545
CIL_0008J8 CIL_0008J8_0001 VISTA 1:236729167-237332656

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000096 TAS sulfur amino acid metabolic process
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005829 TAS cytosol
GO:0006766 TAS vitamin metabolic process
GO:0006767 TAS water-soluble vitamin metabolic process
GO:0006805 TAS xenobiotic metabolic process
GO:0007399 TAS nervous system development
GO:0008270 IEA zinc ion binding
GO:0008705 IEA methionine synthase activity
GO:0008898 IEA S-adenosylmethionine-homocysteine S-methyltransferase activity
GO:0009086 IEA methionine biosynthetic process
GO:0009235 TAS cobalamin metabolic process
GO:0031419 IEA cobalamin binding
GO:0032259 IEA methylation
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042558 IEA pteridine-containing compound metabolic process
GO:0044237 IEA cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039134 MTR 5-methyltetrahydrofolate-homocysteine methyltransferase protein_coding Danio_rerio
ENSMUSG00000021311 Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase protein_coding Mus_musculus

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