C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: regulator of G-protein signaling 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000117152 RGS4 9606 + 1:163068775-163076802 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000367906 RGS4-002 163072044-163074816 protein_coding
  ENST00000367908 RGS4-003 163069361-163076591 protein_coding
  ENST00000367909 RGS4-001 163069145-163076802 protein_coding
  ENST00000421743 RGS4-005 163068775-163076802 protein_coding
  ENST00000491263 RGS4-004 163069363-163076591 processed_transcript
  ENST00000527393 RGS4-006 163068935-163073494 processed_transcript
  ENST00000527809 RGS4-007 163069361-163074755 protein_coding
  ENST00000528938 RGS4-009 163072146-163074427 protein_coding
  ENST00000531057 RGS4-010 163069361-163074708 protein_coding
  ENST00000533019 RGS4-008 163070537-163074343 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000367906ENST00000367908ENST00000367909ENST00000421743ENST00000491263ENST00000527393ENST00000527809ENST00000528938ENST00000531057ENST00000533019
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000367906 N/A N/A N/A N/A 0.263±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000367908 0.493±0.00 1.277±0.00 0.213±0.00 10.008±0.00 0.136±0.03 1.031±0.87 0.188±0.00 N/A 0.177±0.00 0.795±0.00 N/A 2.955±0.00 0.310±0.20 0.480±0.00
ENST00000367909 N/A N/A 0.181±0.00 56.631±11.58 0.321±0.00 N/A N/A N/A 0.260±0.00 0.070±0.00 N/A 1.117±1.23 N/A 0.444±0.00
ENST00000421743 N/A N/A N/A 25.451±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000491263 N/A N/A N/A N/A 0.177±0.00 N/A N/A N/A N/A N/A N/A 0.047±0.00 N/A N/A
ENST00000527393 N/A N/A N/A N/A N/A N/A N/A 0.885±0.00 N/A N/A N/A N/A N/A 0.797±0.00
ENST00000527809 N/A 0.890±0.00 N/A N/A N/A 0.577±0.00 N/A N/A N/A N/A 0.106±0.02 N/A 0.072±0.00 0.434±0.00
ENST00000528938 N/A N/A N/A N/A N/A N/A N/A 0.782±0.00 N/A 0.670±0.00 N/A N/A N/A N/A
ENST00000531057 N/A N/A N/A N/A 1.118±0.00 N/A 1.733±0.00 N/A 0.593±0.00 N/A 0.150±0.00 N/A N/A N/A
ENST00000533019 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.417±0.00 N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000188 TAS inactivation of MAPK activity
GO:0001965 IEA G-protein alpha-subunit binding
GO:0005096 IBA GTPase activator activity
GO:0005516 TAS calmodulin binding
GO:0005737 IBA cytoplasm
GO:0005829 IEA cytosol
GO:0005886 IBA plasma membrane
GO:0008277 TAS:IEA regulation of G-protein coupled receptor protein signaling pathway
GO:0016020 IEA membrane
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0043234 IEA protein complex
GO:0043547 IEA positive regulation of GTPase activity
GO:0045744 IEA negative regulation of G-protein coupled receptor protein signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070047 rgs4 regulator of G-protein signalling 4 protein_coding Danio_rerio
ENSMUSG00000038530 Rgs4 regulator of G-protein signaling 4 protein_coding Mus_musculus

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