C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000117461 PIK3R3 9606 - 1:46040140-46133036 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262741 PIK3R3-001 46040140-46132642 protein_coding
  ENST00000372006 PIK3R3-002 46040140-46132794 protein_coding
  ENST00000420542 PIK3R3-201 46040142-46133036 protein_coding
  ENST00000423209 PIK3R3-004 46043662-46132616 protein_coding
  ENST00000425892 PIK3R3-005 46066056-46132913 protein_coding
  ENST00000488808 PIK3R3-003 46042641-46057434 processed_transcript
  ENST00000493202 PIK3R3-006 46061950-46132911 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262741ENST00000372006ENST00000420542ENST00000423209ENST00000425892ENST00000488808ENST00000493202
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262741 33.465±0.00 6.892±0.00 2.019±0.00 3.841±2.61 3.901±2.25 5.561±4.52 6.220±3.96 3.500±0.00 1.334±1.00 4.717±0.49 2.135±0.88 2.231±0.84 3.362±1.04 17.219±3.52
ENST00000372006 N/A 2.633±0.00 N/A 4.217±0.00 1.185±0.00 N/A N/A 4.650±0.00 1.034±0.00 N/A N/A 1.050±0.53 1.888±0.08 4.286±0.00
ENST00000420542 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.705±0.00 N/A N/A
ENST00000423209 N/A N/A 1.001±0.00 N/A 1.781±0.00 N/A N/A N/A 2.246±0.00 2.858±0.00 2.435±0.00 N/A N/A N/A
ENST00000425892 N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.296±0.00 N/A N/A N/A N/A
ENST00000488808 N/A N/A N/A N/A N/A N/A N/A 0.144±0.00 N/A N/A N/A N/A N/A N/A
ENST00000493202 N/A N/A 3.490±0.00 N/A 8.909±0.00 N/A N/A N/A N/A N/A 2.484±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0005942 IEA phosphatidylinositol 3-kinase complex
GO:0006644 TAS phospholipid metabolic process
GO:0006661 TAS phosphatidylinositol biosynthetic process
GO:0008286 TAS insulin receptor signaling pathway
GO:0016303 TAS 1-phosphatidylinositol-3-kinase activity
GO:0035014 IEA phosphatidylinositol 3-kinase regulator activity
GO:0036092 TAS phosphatidylinositol-3-phosphate biosynthetic process
GO:0043551 IEA regulation of phosphatidylinositol 3-kinase activity
GO:0044281 TAS small molecule metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034409 pik3r3b phosphoinositide-3-kinase, regulatory subunit 3b (gamma) protein_coding Danio_rerio
ENSMUSG00000028698 Pik3r3 phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55) protein_coding Mus_musculus

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