C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hydroxysteroid (11-beta) dehydrogenase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000117594 HSD11B1 9606 + 1:209686178-209734950 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261465 HSD11B1-002 209686269-209734478 protein_coding
  ENST00000367027 HSD11B1-001 209704846-209734950 protein_coding
  ENST00000367028 HSD11B1-201 209686180-209734949 protein_coding
  ENST00000615289 HSD11B1-003 209686178-209732465 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261465ENST00000367027ENST00000367028ENST00000615289
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261465 1.667±0.00 0.709±0.00 N/A 7.048±0.00 8.803±6.13 1.992±1.60 0.713±0.33 1.905±0.00 22.917±20.63 12.849±0.00 0.828±0.00 6.513±6.23 13.638±0.00 1.373±0.91
ENST00000367027 1.608±0.00 0.382±0.00 0.092±0.00 2.959±0.07 5.182±3.01 1.192±0.31 0.590±0.17 113.230±0.00 9.659±8.63 4.813±3.06 0.305±0.08 10.040±11.77 21.261±11.79 1.781±0.07
ENST00000367028 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.570±0.00 N/A N/A
ENST00000615289 N/A N/A 1.191±0.00 N/A N/A N/A N/A 1.310±0.00 N/A 0.749±0.00 N/A 2.835±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089N CIL_00089N_0001 VISTA 1:209189712-209790617
CIL_0007ZL CIL_0007ZL_0001 VISTA 1:209515705-210116479

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003845 TAS 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006704 TAS glucocorticoid biosynthetic process
GO:0008152 IEA metabolic process
GO:0008202 TAS steroid metabolic process
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0016491 IEA oxidoreductase activity
GO:0030324 IEA lung development
GO:0044281 TAS small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0070524 IEA 11-beta-hydroxysteroid dehydrogenase (NADP+) activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000016194 Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 protein_coding Mus_musculus

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