C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interferon regulatory factor 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000117595 IRF6 9606 - 1:209785623-209806175 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000367021 IRF6-001 209785691-209806044 protein_coding
  ENST00000456314 IRF6-002 209790726-209802166 protein_coding
  ENST00000464698 IRF6-003 209790738-209792714 retained_intron
  ENST00000542854 IRF6-201 209785623-209806175 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000367021ENST00000456314ENST00000542854
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000367021 0.403±0.00 0.714±0.00 2.610±0.00 0.208±0.00 2.804±0.74 1.348±0.94 8.259±0.00 7.041±0.00 2.047±0.59 4.256±2.64 0.103±0.00 3.760±2.90 10.030±0.94 2.040±1.12
ENST00000456314 0.498±0.00 N/A 1.978±0.00 N/A N/A N/A N/A N/A N/A 1.357±0.00 0.077±0.00 N/A N/A N/A
ENST00000542854 0.258±0.00 0.115±0.00 N/A 0.120±0.06 2.407±0.41 2.285±0.52 0.316±0.00 1.717±0.00 1.589±1.14 0.873±0.46 N/A 2.298±1.78 3.625±1.81 1.365±0.75

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089N CIL_00089N_0001 VISTA 1:209189712-209790617
CIL_0007ZL CIL_0007ZL_0001 VISTA 1:209515705-210116479

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000975 IEA regulatory region DNA binding
GO:0003677 ISS DNA binding
GO:0003700 ISS:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007050 IDA cell cycle arrest
GO:0008285 IDA negative regulation of cell proliferation
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0030216 IEA keratinocyte differentiation
GO:0043588 IEA skin development
GO:0043616 IEA keratinocyte proliferation
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0048468 IEA cell development
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0060644 ISS mammary gland epithelial cell differentiation
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043296 irf6 interferon regulatory factor 6 protein_coding Danio_rerio
ENSMUSG00000026638 Irf6 interferon regulatory factor 6 protein_coding Mus_musculus

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