C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: growth hormone releasing hormone
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000118702 GHRH 9606 - 20:37251082-37261835 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000237527 GHRH-201 37251086-37256896 protein_coding
  ENST00000373611 GHRH-002 37251160-37256889 protein_coding
  ENST00000373614 GHRH-001 37251082-37261835 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartPlacentaTestisENST00000237527ENST00000373611
Transcript ID Brain Heart Placenta Testis
ENST00000237527 0.200±0.00 0.349±0.00 N/A N/A
ENST00000373611 0.178±0.00 N/A 0.095±0.00 0.218±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004Y1 CIL_0004Y1_0001 CGP 20:37178410-37261835
CIL_0006YH CIL_0006YH_0001 CGP 20:37251082-37317260

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005179 IEA hormone activity
GO:0005515 IEA protein binding
GO:0005576 NAS:IEA extracellular region
GO:0005615 ISS extracellular space
GO:0007189 ISS adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0008284 IDA positive regulation of cell proliferation
GO:0016608 IDA growth hormone-releasing hormone activity
GO:0019933 IDA cAMP-mediated signaling
GO:0021984 ISS adenohypophysis development
GO:0030252 IDA growth hormone secretion
GO:0030819 IDA positive regulation of cAMP biosynthetic process
GO:0031770 IPI growth hormone-releasing hormone receptor binding
GO:0032094 ISS response to food
GO:0040018 IMP positive regulation of multicellular organism growth
GO:0043195 ISS terminal bouton
GO:0043568 NAS positive regulation of insulin-like growth factor receptor signaling pathway
GO:0046005 NAS positive regulation of circadian sleep/wake cycle, REM sleep
GO:0046887 IEA positive regulation of hormone secretion
GO:0060124 NAS positive regulation of growth hormone secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000027643 Ghrh growth hormone releasing hormone protein_coding Mus_musculus

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