C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tumor necrosis factor receptor superfamily, member 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000120949 TNFRSF8 9606 + 1:12063377-12144207 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263932 TNFRSF8-001 12063377-12144207 protein_coding
  ENST00000413146 TNFRSF8-002 12125899-12144207 protein_coding
  ENST00000417814 TNFRSF8-201 12063377-12144205 protein_coding
  ENST00000479933 TNFRSF8-004 12125934-12144207 processed_transcript
  ENST00000514649 TNFRSF8-003 12063470-12143117 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000263932ENST00000413146ENST00000417814ENST00000479933ENST00000514649
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000263932 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.362±0.00 0.676±0.00 N/A
ENST00000413146 0.615±0.00 0.685±0.00 N/A 0.165±0.00 0.952±0.00 1.029±0.00 N/A 0.137±0.00 N/A N/A 0.663±0.11 1.208±0.58 1.050±0.75
ENST00000417814 N/A N/A N/A N/A 0.143±0.00 N/A N/A N/A N/A 0.097±0.00 N/A 0.412±0.13 N/A
ENST00000479933 0.441±0.00 0.525±0.00 N/A N/A 0.139±0.00 N/A 0.067±0.00 N/A 0.362±0.35 0.425±0.08 N/A N/A N/A
ENST00000514649 N/A N/A 0.027±0.00 0.047±0.00 N/A 0.295±0.00 0.032±0.00 N/A N/A N/A N/A 0.576±0.15 0.964±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00087H CIL_00087H_0001 VISTA 1:11580820-12184055

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004888 IEA transmembrane signaling receptor activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0007165 IEA signal transduction
GO:0008285 TAS negative regulation of cell proliferation
GO:0016021 IEA integral component of membrane
GO:0042535 IDA positive regulation of tumor necrosis factor biosynthetic process
GO:0043065 IDA positive regulation of apoptotic process
GO:0045556 IDA positive regulation of TRAIL biosynthetic process
GO:0070062 IDA extracellular vesicular exosome
GO:0071260 IEP cellular response to mechanical stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000028602 Tnfrsf8 tumor necrosis factor receptor superfamily, member 8 protein_coding Mus_musculus

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