C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: BCL2-like 14 (apoptosis facilitator)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000121380 BCL2L14 9606 + 12:12049844-12211084 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000266434 BCL2L14-003 12071468-12099695 protein_coding
  ENST00000298566 BCL2L14-002 12079299-12211084 nonsense_mediated_decay
  ENST00000308721 BCL2L14-001 12070939-12099695 protein_coding
  ENST00000396367 BCL2L14-012 12071468-12099695 protein_coding
  ENST00000461264 BCL2L14-005 12049891-12079671 protein_coding
  ENST00000464885 BCL2L14-004 12049864-12079478 protein_coding
  ENST00000466531 BCL2L14-006 12070939-12078067 processed_transcript
  ENST00000479717 BCL2L14-007 12070935-12071840 processed_transcript
  ENST00000484949 BCL2L14-008 12049864-12055784 processed_transcript
  ENST00000545463 BCL2L14-009 12049863-12072360 processed_transcript
  ENST00000586576 BCL2L14-010 12049861-12099684 protein_coding
  ENST00000588270 BCL2L14-013 12079253-12087309 protein_coding
  ENST00000589718 BCL2L14-011 12049844-12099684 protein_coding
  ENST00000591235 BCL2L14-014 12049861-12072336 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000266434ENST00000298566ENST00000308721ENST00000396367ENST00000466531ENST00000479717ENST00000484949ENST00000586576ENST00000588270ENST00000589718
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000266434 N/A N/A N/A N/A 0.987±0.00 N/A N/A N/A N/A N/A 0.548±0.00 N/A N/A
ENST00000298566 N/A N/A 0.022±0.00 0.446±0.00 N/A N/A 0.059±0.03 N/A N/A N/A N/A 0.155±0.00 N/A
ENST00000308721 N/A N/A N/A 0.906±0.00 2.141±0.84 N/A 0.066±0.00 0.238±0.00 N/A N/A 2.069±1.07 N/A N/A
ENST00000396367 N/A N/A N/A 0.626±0.00 N/A N/A 0.057±0.00 0.116±0.00 0.290±0.00 N/A 0.702±0.23 0.018±0.00 N/A
ENST00000466531 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.103±0.42 N/A N/A
ENST00000479717 N/A N/A N/A N/A N/A N/A N/A 0.162±0.00 N/A N/A N/A N/A N/A
ENST00000484949 0.087±0.00 0.351±0.00 0.131±0.00 0.201±0.00 N/A 0.189±0.00 0.253±0.00 0.155±0.00 0.248±0.00 0.036±0.00 0.040±0.00 N/A N/A
ENST00000586576 N/A N/A N/A N/A N/A N/A 0.089±0.00 N/A N/A N/A N/A N/A N/A
ENST00000588270 0.145±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000589718 N/A 0.103±0.00 N/A N/A N/A N/A N/A N/A 0.249±0.00 N/A 0.057±0.00 0.049±0.00 12.711±2.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000K4 CIL_0000K4_0001 CGP 12:11649854-12211084
CIL_0003HK CIL_0003HK_0001 CGP 12:12049844-12267012

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0006915 IDA apoptotic process
GO:0016020 IEA membrane
GO:0019901 IPI protein kinase binding
GO:0042981 IEA regulation of apoptotic process
GO:0043229 IDA intracellular organelle
GO:2001238 IDA positive regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090401 CABZ01020840.1 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000030200 Bcl2l14 BCL2-like 14 (apoptosis facilitator) protein_coding Mus_musculus

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