C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lymphocyte transmembrane adaptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000122188 LAX1 9606 + 1:203765176-203776233 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000367215 LAX1-001 203769638-203776233 processed_transcript
  ENST00000367217 LAX1-003 203765177-203774722 protein_coding
  ENST00000442561 LAX1-002 203765176-203776117 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000367215ENST00000367217ENST00000442561
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000367215 0.139±0.00 0.036±0.00 N/A N/A 0.097±0.00 N/A 0.154±0.00 0.309±0.00 0.007±0.00 0.084±0.00 0.064±0.01 N/A
ENST00000367217 N/A N/A 1.453±0.00 N/A 0.019±0.00 0.039±0.00 N/A N/A 0.069±0.00 N/A N/A N/A
ENST00000442561 0.062±0.00 N/A 0.893±0.00 0.329±0.18 N/A 0.057±0.00 0.440±0.00 0.754±0.13 N/A 0.169±0.07 0.066±0.00 0.044±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00096T CIL_00096T_0001 VISTA 1:203391843-203993678
CIL_0008W2 CIL_0008W2_0001 VISTA 1:203635137-204239984

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000188 IMP inactivation of MAPK activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0006955 IDA immune response
GO:0016020 IDA membrane
GO:0016021 IDA integral component of membrane
GO:0019901 IDA protein kinase binding
GO:0035556 IDA intracellular signal transduction
GO:0042113 IDA B cell activation
GO:0042169 IDA SH2 domain binding
GO:0046649 IEA lymphocyte activation
GO:0048305 IEA immunoglobulin secretion
GO:0050851 IEA antigen receptor-mediated signaling pathway
GO:0050868 IDA negative regulation of T cell activation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000051998 Lax1 lymphocyte transmembrane adaptor 1 protein_coding Mus_musculus

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