C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: plasminogen
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000122194 PLG 9606 + 6:160702238-160753315 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000297289 PLG-003 160702260-160731231 processed_transcript
  ENST00000308192 PLG-001 160702242-160753306 protein_coding
  ENST00000366924 PLG-002 160702238-160711883 protein_coding
  ENST00000418964 PLG-006 160702246-160713026 protein_coding
  ENST00000461414 PLG-008 160739168-160753315 processed_transcript
  ENST00000462918 PLG-004 160702268-160713376 processed_transcript
  ENST00000467466 PLG-012 160738435-160752253 retained_intron
  ENST00000471691 PLG-007 160706375-160708317 retained_intron
  ENST00000483038 PLG-005 160702292-160708609 processed_transcript
  ENST00000484367 PLG-009 160705388-160712279 retained_intron
  ENST00000493435 PLG-011 160730740-160731833 retained_intron
  ENST00000494325 PLG-010 160706110-160711572 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000308192ENST00000461414ENST00000462918ENST00000467466ENST00000471691ENST00000483038ENST00000484367ENST00000494325
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000308192 N/A N/A 28.407±0.00 0.068±0.00 1.095±0.00 N/A N/A 266.071±253.15 201.114±200.95 N/A 0.075±0.00 N/A N/A 0.098±0.00
ENST00000461414 0.134±0.00 1.339±0.00 N/A 0.120±0.00 0.300±0.00 N/A 0.141±0.00 19.426±0.00 N/A 0.103±0.00 0.539±0.00 0.899±0.32 1.203±0.78 1.297±0.00
ENST00000462918 0.045±0.00 N/A N/A 0.058±0.00 0.080±0.00 0.085±0.00 N/A N/A N/A 0.132±0.00 N/A N/A N/A N/A
ENST00000467466 N/A N/A N/A 0.190±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000471691 N/A N/A N/A 0.149±0.00 N/A 0.540±0.00 0.036±0.00 N/A 0.615±0.00 0.041±0.00 N/A 0.549±0.00 N/A N/A
ENST00000483038 N/A N/A N/A 0.182±0.00 N/A N/A 0.045±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000484367 N/A 0.097±0.00 N/A 0.036±0.00 0.027±0.00 N/A N/A N/A N/A N/A N/A 0.059±0.02 0.012±0.00 0.103±0.01
ENST00000494325 0.055±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002576 TAS platelet degranulation
GO:0003824 IEA catalytic activity
GO:0004175 IEA endopeptidase activity
GO:0004252 IDA:IEA serine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005886 TAS plasma membrane
GO:0006508 IEA proteolysis
GO:0007596 IMP blood coagulation
GO:0008236 TAS serine-type peptidase activity
GO:0008285 TAS negative regulation of cell proliferation
GO:0009986 IDA cell surface
GO:0010812 IDA negative regulation of cell-substrate adhesion
GO:0019897 IEA extrinsic component of plasma membrane
GO:0019904 IPI protein domain specific binding
GO:0022617 IDA extracellular matrix disassembly
GO:0030168 TAS platelet activation
GO:0030198 TAS extracellular matrix organization
GO:0031093 TAS platelet alpha granule lumen
GO:0031232 IDA extrinsic component of external side of plasma membrane
GO:0034185 IPI apolipoprotein binding
GO:0042246 IEA tissue regeneration
GO:0042730 TAS fibrinolysis
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0044267 TAS cellular protein metabolic process
GO:0045445 IEA myoblast differentiation
GO:0046716 IEA muscle cell cellular homeostasis
GO:0048771 IEA tissue remodeling
GO:0051603 IEA proteolysis involved in cellular protein catabolic process
GO:0051918 IDA negative regulation of fibrinolysis
GO:0051919 IDA positive regulation of fibrinolysis
GO:0060707 IEA trophoblast giant cell differentiation
GO:0060716 IEA labyrinthine layer blood vessel development
GO:0070062 IDA extracellular vesicular exosome
GO:0071674 IEA mononuclear cell migration
GO:0072562 IDA blood microparticle
GO:2000048 TAS negative regulation of cell-cell adhesion mediated by cadherin

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000023111 plg plasminogen protein_coding Danio_rerio
ENSMUSG00000059481 Plg plasminogen protein_coding Mus_musculus

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