C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: early growth response 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000122877 EGR2 9606 - 10:62811996-62919900 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000242480 EGR2-001 62811996-62816355 protein_coding
  ENST00000411732 EGR2-201 62812003-62816366 protein_coding
  ENST00000439032 EGR2-202 62812003-62819167 protein_coding
  ENST00000493899 EGR2-002 62814433-62919900 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000242480ENST00000411732ENST00000439032
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000242480 0.614±0.00 0.916±0.00 0.440±0.00 0.400±0.00 5.623±0.00 N/A 0.143±0.00 0.198±0.09 0.429±0.00 0.565±0.12 N/A 3.068±2.23 0.902±0.28 1.958±1.81
ENST00000411732 0.687±0.00 0.187±0.00 0.660±0.00 0.695±0.01 1.548±0.02 0.276±0.00 0.094±0.00 N/A N/A 0.828±0.56 0.233±0.00 1.369±0.62 0.522±0.00 0.244±0.00
ENST00000439032 N/A N/A N/A 1.059±0.00 1.239±0.07 0.530±0.00 0.093±0.00 0.267±0.00 0.112±0.00 0.496±0.00 N/A 4.441±4.06 0.659±0.00 1.722±1.33

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002NR CIL_0002NR_0002 CGP 10:62804857-62919900
CIL_0004Q4 CIL_0004Q4_0002 CGP 10:62811996-63155031

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001102 ISS RNA polymerase II activating transcription factor binding
GO:0003677 IEA DNA binding
GO:0003682 ISS chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 ISS transcription from RNA polymerase II promoter
GO:0006611 ISS protein export from nucleus
GO:0007420 TAS brain development
GO:0007422 TAS peripheral nervous system development
GO:0007611 IEA learning or memory
GO:0007622 IEA rhythmic behavior
GO:0008045 IEA motor neuron axon guidance
GO:0008219 IEA cell death
GO:0014037 IEA Schwann cell differentiation
GO:0016874 IEA ligase activity
GO:0016925 IEA protein sumoylation
GO:0021569 IEA rhombomere 3 development
GO:0021612 IEA facial nerve structural organization
GO:0021660 IEA rhombomere 3 formation
GO:0021666 IEA rhombomere 5 formation
GO:0030278 IEA regulation of ossification
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032868 IEA response to insulin
GO:0035284 IEA brain segmentation
GO:0035914 IBA skeletal muscle cell differentiation
GO:0042552 IBA myelination
GO:0043066 IBA negative regulation of apoptotic process
GO:0044212 ISS transcription regulatory region DNA binding
GO:0045444 ISS fat cell differentiation
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048168 IBA regulation of neuronal synaptic plasticity
GO:0071310 IEA cellular response to organic substance
GO:0071320 IBA cellular response to cAMP
GO:0071371 IBA cellular response to gonadotropin stimulus
GO:0071837 IEA HMG box domain binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044098 egr2a early growth response 2a protein_coding Danio_rerio
ENSMUSG00000037868 Egr2 early growth response 2 protein_coding Mus_musculus

Loading