C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: WW domain containing E3 ubiquitin protein ligase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000123124 WWP1 9606 + 8:86342738-86478420 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265428 WWP1-201 86374041-86467476 protein_coding
  ENST00000517970 WWP1-001 86342738-86468503 protein_coding
  ENST00000518683 WWP1-002 86380817-86448497 retained_intron
  ENST00000520374 WWP1-004 86405055-86430703 processed_transcript
  ENST00000520453 WWP1-006 86435458-86448435 protein_coding
  ENST00000520521 WWP1-009 86457989-86461742 retained_intron
  ENST00000520798 WWP1-010 86461227-86478420 protein_coding
  ENST00000521079 WWP1-005 86417223-86431665 processed_transcript
  ENST00000521997 WWP1-007 86435611-86452581 retained_intron
  ENST00000523863 WWP1-003 86342774-86387026 processed_transcript
  ENST00000524036 WWP1-008 86442272-86452596 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265428ENST00000517970
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265428 8.378±0.00 7.041±0.00 6.848±0.00 3.493±1.47 9.500±2.31 7.336±1.82 13.936±6.71 11.081±3.84 7.897±0.42 8.169±1.09 12.291±0.14 10.175±2.16 5.847±0.79 8.310±0.42
ENST00000517970 4.253±0.00 4.922±0.00 4.861±0.00 2.724±0.00 6.238±0.03 5.522±0.27 6.576±2.85 9.870±2.89 6.017±0.21 5.125±1.32 5.077±0.80 4.435±1.07 3.528±0.08 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00052S CIL_00052S_0002 CGP 8:86342738-86514357

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000151 NAS ubiquitin ligase complex
GO:0004842 IEA:IBA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IBA nucleus
GO:0005737 IBA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0007165 NAS signal transduction
GO:0007417 NAS central nervous system development
GO:0016567 IEA:TAS protein ubiquitination
GO:0016874 IEA ligase activity
GO:0034220 TAS ion transmembrane transport
GO:0042787 IBA protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043161 IEA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0046718 TAS viral entry into host cell
GO:0055085 TAS transmembrane transport
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000097537 WWP1 WW domain containing E3 ubiquitin protein ligase 1 protein_coding Danio_rerio
ENSMUSG00000041058 Wwp1 WW domain containing E3 ubiquitin protein ligase 1 protein_coding Mus_musculus

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