C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: GIPC PDZ domain containing family, member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000123159 GIPC1 9606 - 19:14477760-14496149 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000345425 GIPC1-007 14477762-14496132 protein_coding
  ENST00000393028 GIPC1-201 14477760-14496149 protein_coding
  ENST00000393033 GIPC1-001 14477762-14496132 protein_coding
  ENST00000585606 GIPC1-002 14477764-14480596 retained_intron
  ENST00000586027 GIPC1-005 14478246-14496132 protein_coding
  ENST00000587210 GIPC1-008 14479412-14496132 protein_coding
  ENST00000587811 GIPC1-003 14481747-14483463 retained_intron
  ENST00000587934 GIPC1-009 14482856-14491743 protein_coding
  ENST00000587969 GIPC1-004 14480306-14480896 protein_coding
  ENST00000589497 GIPC1-010 14478256-14496052 nonsense_mediated_decay
  ENST00000589631 GIPC1-012 14478004-14479857 protein_coding
  ENST00000591245 GIPC1-011 14482857-14483445 protein_coding
  ENST00000591349 GIPC1-006 14478246-14496132 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000345425ENST00000393028ENST00000393033ENST00000586027ENST00000587210ENST00000587969ENST00000589497ENST00000589631ENST00000591349
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000345425 9.923±0.00 13.550±0.00 N/A 23.999±0.00 17.950±16.90 26.948±0.00 6.995±0.00 12.391±0.00 3.825±2.71 10.974±0.00 6.689±0.00 7.746±5.74 N/A 12.822±0.00
ENST00000393028 4.978±0.00 N/A N/A N/A N/A 11.200±0.00 4.020±0.00 28.817±0.00 5.707±0.00 18.900±0.00 4.143±0.34 66.473±14.46 31.043±1.20 7.619±2.28
ENST00000393033 8.807±0.00 8.628±0.00 N/A 5.669±3.58 21.562±0.00 10.686±0.00 4.716±3.61 8.461±0.00 1.156±0.00 7.725±6.22 6.481±0.00 20.989±12.89 19.245±7.97 5.580±1.66
ENST00000586027 N/A N/A 1.423±0.00 N/A 1.143±0.00 5.302±0.00 0.346±0.00 N/A 0.584±0.00 N/A N/A 42.330±41.05 23.657±0.00 9.710±0.00
ENST00000587210 N/A N/A 1.510±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000587969 N/A N/A N/A N/A 1.659±0.00 N/A N/A 2.721±0.00 N/A 1.228±0.00 N/A 4.621±0.00 N/A N/A
ENST00000589497 N/A N/A N/A 1.546±0.00 0.716±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000589631 N/A N/A N/A N/A N/A N/A N/A 1.000±0.00 N/A N/A N/A N/A N/A N/A
ENST00000591349 N/A N/A N/A 12.781±0.00 N/A N/A N/A N/A 0.485±0.00 N/A N/A 20.095±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000179 CIL_000179_0002 CGP 19:14477760-14529770

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 ISS actin binding
GO:0005102 IPI receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005737 ISS cytoplasm
GO:0005829 ISS cytosol
GO:0005903 IEA brush border
GO:0005938 IDA cell cortex
GO:0006605 ISS protein targeting
GO:0007186 NAS G-protein coupled receptor signaling pathway
GO:0007268 ISS synaptic transmission
GO:0008021 ISS synaptic vesicle
GO:0012506 ISS vesicle membrane
GO:0014047 ISS glutamate secretion
GO:0016020 ISS membrane
GO:0016023 IDA cytoplasmic membrane-bounded vesicle
GO:0017022 ISS myosin binding
GO:0030139 IEA endocytic vesicle
GO:0030165 IEA PDZ domain binding
GO:0030511 ISS positive regulation of transforming growth factor beta receptor signaling pathway
GO:0031647 ISS regulation of protein stability
GO:0032435 ISS negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032467 IMP positive regulation of cytokinesis
GO:0042803 ISS protein homodimerization activity
GO:0043197 ISS dendritic spine
GO:0043198 ISS dendritic shaft
GO:0043542 ISS endothelial cell migration
GO:0048167 ISS regulation of synaptic plasticity
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010771 gipc1 GIPC PDZ domain containing family, member 1 protein_coding Danio_rerio
ENSMUSG00000019433 Gipc1 GIPC PDZ domain containing family, member 1 protein_coding Mus_musculus

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