C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serpin peptidase inhibitor, clade B (ovalbumin), member 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000124570 SERPINB6 9606 - 6:2948159-2972165 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000335686 SERPINB6-003 2948159-2971856 protein_coding
  ENST00000380520 SERPINB6-002 2948159-2961327 protein_coding
  ENST00000380524 SERPINB6-001 2948159-2962108 protein_coding
  ENST00000380529 SERPINB6-004 2948159-2971206 protein_coding
  ENST00000380539 SERPINB6-005 2948159-2971305 protein_coding
  ENST00000380546 SERPINB6-006 2948159-2971585 protein_coding
  ENST00000612421 SERPINB6-201 2948160-2971048 protein_coding
  ENST00000616722 SERPINB6-202 2948160-2972165 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000335686ENST00000380520ENST00000380524ENST00000380529ENST00000380539ENST00000380546ENST00000612421
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000335686 10.659±0.00 N/A 2.050±0.00 1.672±0.00 9.414±3.46 10.982±4.16 12.118±5.80 5.404±0.00 5.330±0.00 25.162±0.00 11.743±0.00 25.650±8.63 28.482±8.42 N/A
ENST00000380520 N/A N/A N/A N/A 2.214±0.00 2.255±0.00 N/A N/A N/A 3.237±0.00 N/A 2.301±0.00 N/A N/A
ENST00000380524 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 13.116±0.00 N/A
ENST00000380529 21.748±0.00 21.500±0.00 N/A 23.884±0.00 15.068±0.00 21.731±0.00 41.432±0.00 16.201±0.00 10.225±0.00 55.664±0.00 15.438±0.00 43.459±18.80 25.615±3.81 91.684±44.78
ENST00000380539 25.427±0.00 51.189±0.00 N/A 11.856±5.97 31.700±0.00 34.377±0.00 11.334±5.02 49.583±0.00 6.126±0.27 N/A 10.292±7.21 47.144±10.48 87.954±41.81 77.377±5.61
ENST00000380546 N/A N/A 1.208±0.00 N/A N/A N/A N/A N/A N/A 3.130±0.00 N/A 18.386±10.93 21.291±1.94 N/A
ENST00000612421 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.890±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000160 CIL_000160_0007 CGP 6:2887266-2972165
CIL_00081I CIL_00081I_0001 VISTA 6:2946622-3549686
CIL_00038C CIL_00038C_0001 CGP 6:2948159-3028869

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002020 IPI protease binding
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005615 IEA extracellular space
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0030162 IBA regulation of proteolysis
GO:0043234 IDA protein complex
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014556 serpinb1l3 serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3 protein_coding Danio_rerio
ENSDARG00000057263 zgc:173729 zgc:173729 protein_coding Danio_rerio
ENSDARG00000091801 si:ch73-303g23.4 si:ch73-303g23.4 protein_coding Danio_rerio
ENSDARG00000095830 serpinb1l1 serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1 protein_coding Danio_rerio
ENSDARG00000096888 serpinb1l4 serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 4 protein_coding Danio_rerio
ENSMUSG00000042842 Serpinb6b serine (or cysteine) peptidase inhibitor, clade B, member 6b protein_coding Mus_musculus
ENSMUSG00000047889 Serpinb6d serine (or cysteine) peptidase inhibitor, clade B, member 6d protein_coding Mus_musculus
ENSMUSG00000052180 Serpinb6c serine (or cysteine) peptidase inhibitor, clade B, member 6c protein_coding Mus_musculus
ENSMUSG00000060147 Serpinb6a serine (or cysteine) peptidase inhibitor, clade B, member 6a protein_coding Mus_musculus
ENSMUSG00000069248 Serpinb6e serine (or cysteine) peptidase inhibitor, clade B, member 6e protein_coding Mus_musculus

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