C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SAM pointed domain containing ETS transcription factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000124664 SPDEF 9606 - 6:34537802-34556333 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000374037 SPDEF-001 34537802-34556314 protein_coding
  ENST00000544425 SPDEF-201 34537802-34556333 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLungMuscleOvaryPlacentaTestisENST00000374037ENST00000544425
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Lung Muscle Ovary Placenta Testis
ENST00000374037 N/A N/A 0.560±0.40 3.075±1.96 4.786±2.42 N/A N/A 2.322±0.00 N/A 1.138±0.96 N/A 0.402±0.00
ENST00000544425 0.047±0.00 0.017±0.00 N/A 1.044±0.00 N/A 0.017±0.00 0.038±0.00 0.446±0.00 0.090±0.05 0.849±0.00 0.060±0.02 0.348±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004LR CIL_0004LR_0002 CGP 6:34466061-34556333
CIL_0004LT CIL_0004LT_0002 CGP 6:34537802-34696859

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000981 IBA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005634 IBA:IEA nucleus
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 IBA transcription from RNA polymerase II promoter
GO:0007275 TAS multicellular organismal development
GO:0010454 IEA negative regulation of cell fate commitment
GO:0010455 IEA positive regulation of cell fate commitment
GO:0030154 IBA cell differentiation
GO:0043065 IDA positive regulation of apoptotic process
GO:0043565 IEA sequence-specific DNA binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0060480 IEA lung goblet cell differentiation
GO:0060576 IEA intestinal epithelial cell development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029930 SPDEF SAM pointed domain containing ETS transcription factor protein_coding Danio_rerio
ENSMUSG00000024215 Spdef SAM pointed domain containing ets transcription factor protein_coding Mus_musculus

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