C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAP2A, member of RAS oncogene family
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000125249 RAP2A 9606 + 13:97434222-97469128 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000245304 RAP2A-001 97434222-97469128 protein_coding
  ENST00000476869 RAP2A-002 97434471-97464710 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000245304ENST00000476869
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000245304 0.647±0.00 1.507±0.00 9.678±0.00 4.172±0.00 1.857±0.00 1.800±0.00 1.661±0.00 2.726±1.17 4.140±0.00 1.872±0.99 3.129±1.95 3.162±3.48 2.123±0.00
ENST00000476869 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.013±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00041S CIL_00041S_0001 CGP 13:97221434-97469128
CIL_0000O3 CIL_0000O3_0001 CGP 13:97434222-98024297

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 IDA:IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005829 IEA cytosol
GO:0006184 IEA GTP catabolic process
GO:0006886 IEA intracellular protein transport
GO:0006913 IEA nucleocytoplasmic transport
GO:0007165 IEA signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0030336 IEA negative regulation of cell migration
GO:0031532 IDA actin cytoskeleton reorganization
GO:0031954 IDA positive regulation of protein autophosphorylation
GO:0032486 ISS Rap protein signal transduction
GO:0034613 IDA cellular protein localization
GO:0045184 IDA establishment of protein localization
GO:0046328 IDA regulation of JNK cascade
GO:0048814 IDA regulation of dendrite morphogenesis
GO:0055037 IDA recycling endosome
GO:0055038 IDA recycling endosome membrane
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000051615 Rap2a RAS related protein 2a protein_coding Mus_musculus

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