C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: caseinolytic mitochondrial matrix peptidase proteolytic subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000125656 CLPP 9606 + 19:6361452-6368908 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000245816 CLPP-001 6361452-6368908 protein_coding
  ENST00000594780 CLPP-002 6361674-6365190 retained_intron
  ENST00000596070 CLPP-003 6361565-6368707 retained_intron
  ENST00000596149 CLPP-005 6361804-6368754 protein_coding
  ENST00000596605 CLPP-004 6361863-6368902 protein_coding
  ENST00000597326 CLPP-006 6361747-6368545 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000245816ENST00000594780ENST00000596070ENST00000596149ENST00000596605ENST00000597326
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000245816 25.895±0.00 29.368±0.00 N/A 10.829±0.00 14.038±13.38 12.430±10.59 6.522±5.90 18.991±13.64 21.805±0.00 21.035±0.00 38.882±0.00 15.733±13.68 27.203±10.47 16.164±6.18
ENST00000594780 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.535±0.00 N/A N/A N/A N/A
ENST00000596070 N/A N/A 1.486±0.00 N/A 1.392±0.00 N/A N/A N/A N/A 0.578±0.00 N/A N/A N/A N/A
ENST00000596149 12.057±0.00 14.248±0.00 N/A 11.407±7.15 15.928±0.00 15.970±0.00 7.780±6.59 7.894±0.00 13.101±9.94 17.574±0.00 26.075±12.11 14.451±3.97 8.529±0.48 23.929±4.70
ENST00000596605 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.820±0.00
ENST00000597326 12.349±0.00 N/A 16.215±0.00 20.082±0.00 3.098±0.00 5.855±0.00 6.541±0.00 26.969±0.00 4.656±0.00 6.918±0.00 59.947±0.00 3.051±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005OI CIL_0005OI_0001 CGP 19:6306142-6368908
CIL_0005OH CIL_0005OH_0001 CGP 19:6361452-6375251

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004252 IEA:IDA serine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005739 IDA mitochondrion
GO:0005759 IDA mitochondrial matrix
GO:0006508 IEA proteolysis
GO:0008233 TAS peptidase activity
GO:0009368 IDA endopeptidase Clp complex
GO:0042802 IEA identical protein binding
GO:0051260 IEA protein homooligomerization
GO:0051603 IDA proteolysis involved in cellular protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020679 clpp ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli) protein_coding Danio_rerio
ENSMUSG00000002660 Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit protein_coding Mus_musculus

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