C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CD70 molecule
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000125726 CD70 9606 - 19:6583183-6604103 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000245903 CD70-001 6585839-6591152 protein_coding
  ENST00000423145 CD70-003 6583183-6591139 protein_coding
  ENST00000597430 CD70-002 6590103-6604103 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000245903ENST00000423145ENST00000597430
Transcript ID Adipose Adrenal Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000245903 0.361±0.00 0.333±0.00 0.166±0.00 0.041±0.00 0.029±0.00 0.122±0.00 0.748±0.00 1.923±0.00 0.070±0.06 0.080±0.00 0.147±0.00
ENST00000423145 N/A 0.393±0.00 0.237±0.00 0.213±0.00 N/A N/A N/A N/A 0.073±0.02 0.378±0.00 N/A
ENST00000597430 N/A N/A N/A N/A N/A N/A N/A N/A 0.124±0.00 0.223±0.00 0.195±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006KW CIL_0006KW_0001 CGP 19:6530999-6604103
CIL_0004VU CIL_0004VU_0001 CGP 19:6583183-6670588

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002020 IPI protease binding
GO:0005102 TAS receptor binding
GO:0005125 IEA cytokine activity
GO:0005164 IEA tumor necrosis factor receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005615 IEA extracellular space
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006955 IEA immune response
GO:0007165 TAS signal transduction
GO:0007267 TAS cell-cell signaling
GO:0008283 TAS cell proliferation
GO:0016020 IEA membrane
GO:0070062 IDA extracellular vesicular exosome
GO:0097191 IDA extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000019489 Cd70 CD70 antigen protein_coding Mus_musculus

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