C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tumor necrosis factor (ligand) superfamily, member 14
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000125735 TNFSF14 9606 - 19:6661253-6670588 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000245912 TNFSF14-002 6661253-6670117 protein_coding
  ENST00000599359 TNFSF14-001 6664555-6670588 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000245912ENST00000599359
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000245912 0.156±0.00 1.687±0.00 0.036±0.00 0.247±0.05 0.276±0.22 0.114±0.00 0.498±0.17 1.290±1.14 0.398±0.20 0.091±0.04 0.297±0.19 0.156±0.03 0.171±0.10
ENST00000599359 N/A N/A 0.188±0.00 0.129±0.00 0.370±0.00 N/A N/A N/A N/A 0.037±0.00 N/A 0.242±0.00 0.168±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004VU CIL_0004VU_0001 CGP 19:6583183-6670588
CIL_0004C9 CIL_0004C9_0001 CGP 19:6661253-6730562

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005102 IPI receptor binding
GO:0005125 IEA cytokine activity
GO:0005164 IEA tumor necrosis factor receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006915 TAS apoptotic process
GO:0006955 IEA immune response
GO:0007165 NAS signal transduction
GO:0008588 IDA release of cytoplasmic sequestered NF-kappaB
GO:0010820 IEA positive regulation of T cell chemotaxis
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0031295 IEA T cell costimulation
GO:0042098 NAS T cell proliferation
GO:0042110 NAS T cell activation
GO:0043027 IDA cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043029 NAS T cell homeostasis
GO:0043154 IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045663 IEA positive regulation of myoblast differentiation
GO:0071260 IEP cellular response to mechanical stimulus
GO:1901741 IEA positive regulation of myoblast fusion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000005824 Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 protein_coding Mus_musculus

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