C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000125968 ID1 9606 + 20:31605283-31606515 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000376105 ID1-002 31605283-31606515 protein_coding
  ENST00000376112 ID1-001 31605283-31606515 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000376105ENST00000376112
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000376105 1.049±0.00 38.626±0.00 N/A 1.188±0.00 10.545±0.00 2.228±0.40 6.067±0.00 9.695±0.00 N/A 5.131±3.14 1.365±0.00 15.562±10.68 N/A 2.222±0.00
ENST00000376112 6.085±0.00 68.157±0.00 7.776±0.00 8.184±2.86 19.815±9.22 16.211±5.01 31.404±19.34 28.646±20.37 77.030±43.90 45.416±32.36 9.258±0.01 39.750±21.95 89.865±23.13 10.637±4.40

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008K5 CIL_0008K5_0001 VISTA 20:31303913-31904751
CIL_00089Z CIL_00089Z_0001 VISTA 20:31373735-31977079
CIL_0008N4 CIL_0008N4_0001 VISTA 20:31410024-32010895
CIL_0001A1 CIL_0001A1_0001 CGP 20:31605283-31645006

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001525 TAS angiogenesis
GO:0001886 IEA endothelial cell morphogenesis
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0006351 IEA transcription, DNA-templated
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007507 IEA heart development
GO:0007623 IEA circadian rhythm
GO:0010621 TAS negative regulation of transcription by transcription factor localization
GO:0030509 IEA BMP signaling pathway
GO:0031648 IEA protein destabilization
GO:0032963 IEA collagen metabolic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0043392 IEA negative regulation of DNA binding
GO:0043408 IEA regulation of MAPK cascade
GO:0043433 IDA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043534 TAS blood vessel endothelial cell migration
GO:0045668 IEA negative regulation of osteoblast differentiation
GO:0045765 IEA regulation of angiogenesis
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046677 IEA response to antibiotic
GO:0046983 IEA protein dimerization activity
GO:0048511 IEA rhythmic process
GO:0048514 TAS blood vessel morphogenesis
GO:0060425 IEA lung morphogenesis
GO:0060426 IEA lung vasculature development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040764 id1 inhibitor of DNA binding 1 protein_coding Danio_rerio
ENSMUSG00000042745 Id1 inhibitor of DNA binding 1 protein_coding Mus_musculus

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