C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin-like modifier activating enzyme 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000126261 UBA2 9606 + 19:34428352-34471251 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000246548 UBA2-001 34428363-34471251 protein_coding
  ENST00000439527 UBA2-003 34428876-34469890 protein_coding
  ENST00000586313 UBA2-002 34428359-34464131 nonsense_mediated_decay
  ENST00000588585 UBA2-007 34467025-34469116 processed_transcript
  ENST00000590048 UBA2-005 34428373-34450364 protein_coding
  ENST00000591016 UBA2-009 34450284-34464119 protein_coding
  ENST00000592672 UBA2-004 34433260-34438743 retained_intron
  ENST00000592791 UBA2-008 34458714-34469398 protein_coding
  ENST00000592841 UBA2-011 34428484-34432033 retained_intron
  ENST00000607361 UBA2-012 34428352-34438764 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000246548ENST00000439527ENST00000586313ENST00000590048ENST00000592791ENST00000592841
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000246548 4.168±0.00 9.076±0.00 0.588±0.00 1.512±0.44 7.241±0.00 N/A N/A 2.839±1.98 1.652±0.38 2.555±0.37 1.584±0.00 5.114±1.09 3.036±0.68 7.104±0.00
ENST00000439527 N/A 16.162±0.00 N/A 7.412±4.99 16.251±13.22 2.258±0.00 1.639±0.75 N/A N/A N/A 3.712±0.00 20.939±14.98 13.748±10.15 46.631±0.00
ENST00000586313 11.342±0.00 N/A 2.443±0.00 8.786±0.00 N/A 10.819±1.83 N/A 4.591±0.00 N/A N/A 5.174±0.00 8.218±0.00 6.236±1.12 N/A
ENST00000590048 N/A N/A N/A N/A N/A 10.902±0.00 N/A N/A N/A N/A 5.428±0.00 N/A N/A N/A
ENST00000592791 N/A N/A 3.717±0.00 4.541±0.00 12.581±0.00 N/A 2.450±0.00 5.288±0.00 7.155±0.00 8.335±0.00 3.187±0.00 N/A N/A N/A
ENST00000592841 N/A N/A N/A N/A N/A N/A 11.339±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005654 TAS nucleoplasm
GO:0005829 IBA cytosol
GO:0006464 IEA cellular protein modification process
GO:0008047 TAS enzyme activator activity
GO:0008134 IEA transcription factor binding
GO:0008152 IEA metabolic process
GO:0008641 IEA small protein activating enzyme activity
GO:0016874 IEA ligase activity
GO:0016925 IEA protein sumoylation
GO:0019948 IDA SUMO activating enzyme activity
GO:0019950 IBA SMT3-dependent protein catabolic process
GO:0031510 IBA SUMO activating enzyme complex
GO:0043085 TAS positive regulation of catalytic activity
GO:0043687 TAS post-translational protein modification
GO:0044267 TAS cellular protein metabolic process
GO:0046872 IEA metal ion binding
GO:0046982 IPI protein heterodimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077024 uba2 ubiquitin-like modifier activating enzyme 2 protein_coding Danio_rerio
ENSMUSG00000052997 Uba2 ubiquitin-like modifier activating enzyme 2 protein_coding Mus_musculus

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