C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: epidermal growth factor receptor pathway substrate 15-like 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000127527 EPS15L1 9606 - 19:16355239-16472085 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000248070 EPS15L1-006 16361581-16472085 protein_coding
  ENST00000455140 EPS15L1-001 16355239-16472012 protein_coding
  ENST00000535753 EPS15L1-002 16361597-16471976 protein_coding
  ENST00000592031 EPS15L1-003 16361579-16471970 nonsense_mediated_decay
  ENST00000593760 EPS15L1-009 16425092-16471959 nonsense_mediated_decay
  ENST00000594851 EPS15L1-016 16355239-16361953 protein_coding
  ENST00000594975 EPS15L1-004 16361889-16472085 protein_coding
  ENST00000595845 EPS15L1-013 16441511-16471966 retained_intron
  ENST00000596037 EPS15L1-010 16428702-16471951 nonsense_mediated_decay
  ENST00000596151 EPS15L1-014 16417439-16421433 retained_intron
  ENST00000597559 EPS15L1-011 16436596-16471975 retained_intron
  ENST00000597937 EPS15L1-007 16400631-16471950 protein_coding
  ENST00000599790 EPS15L1-015 16382989-16403745 protein_coding
  ENST00000602009 EPS15L1-008 16400631-16435296 protein_coding
  ENST00000602022 EPS15L1-005 16355239-16471961 nonsense_mediated_decay
  ENST00000602151 EPS15L1-012 16440653-16471943 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000248070ENST00000455140ENST00000535753ENST00000592031ENST00000594851ENST00000594975ENST00000597937ENST00000602009ENST00000602022
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000248070 N/A N/A N/A N/A 1.565±0.00 N/A 3.494±3.25 N/A N/A N/A N/A 1.768±0.00 2.654±0.25 3.313±0.00
ENST00000455140 3.357±0.00 N/A N/A 6.797±0.00 1.662±0.00 3.602±0.00 9.662±0.00 3.199±0.00 0.934±0.00 2.358±0.00 41.511±0.00 3.985±0.37 N/A 3.880±0.00
ENST00000535753 2.371±0.00 N/A N/A N/A N/A N/A 0.647±0.00 N/A N/A N/A N/A 8.537±0.00 N/A 8.947±0.00
ENST00000592031 N/A 3.104±0.00 N/A 2.360±1.76 1.451±0.00 2.164±0.00 N/A 1.568±0.99 0.865±0.00 4.412±0.00 10.186±0.00 2.539±0.00 N/A N/A
ENST00000594851 N/A 10.452±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000594975 N/A N/A N/A N/A N/A 1.774±0.00 N/A N/A 0.991±0.00 N/A N/A N/A N/A N/A
ENST00000597937 1.599±0.00 N/A 0.872±0.00 N/A 1.374±0.07 1.404±0.16 N/A 0.825±0.33 0.839±0.06 2.726±0.51 0.826±0.00 4.209±2.44 5.621±1.27 1.744±0.00
ENST00000602009 N/A 1.359±0.00 N/A N/A N/A 0.516±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000602022 N/A 3.165±0.00 N/A 4.751±0.00 2.471±0.00 3.677±0.00 N/A 2.143±0.00 N/A N/A N/A 4.939±1.69 3.155±0.00 3.555±0.35

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004DX CIL_0004DX_0002 CGP 19:16324817-16472085
CIL_00072E CIL_00072E_0001 CGP 19:16355239-16496192

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005886 TAS plasma membrane
GO:0006897 IEA endocytosis
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0016020 IDA membrane
GO:0030132 IEA clathrin coat of coated pit
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042670 eps15l1a epidermal growth factor receptor pathway substrate 15-like 1a protein_coding Danio_rerio
ENSDARG00000067989 epidermal growth factor receptor pathway substrate 15-like 1 protein_coding Danio_rerio
ENSMUSG00000006276 Eps15l1 epidermal growth factor receptor pathway substrate 15-like 1 protein_coding Mus_musculus

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