C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000127955 GNAI1 9606 + 7:80133955-80219402 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000351004 GNAI1-001 80134788-80219402 protein_coding
  ENST00000418742 GNAI1-003 80135289-80203832 protein_coding
  ENST00000442586 GNAI1-004 80133955-80135228 protein_coding
  ENST00000447650 GNAI1-006 80187059-80189209 protein_coding
  ENST00000457358 GNAI1-002 80135755-80217861 protein_coding
  ENST00000490206 GNAI1-005 80134498-80189232 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000351004ENST00000418742ENST00000457358ENST00000490206
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000351004 16.036±0.00 4.494±0.00 0.828±0.00 16.645±6.53 9.155±5.77 6.264±4.60 1.053±0.92 7.322±5.70 3.139±0.84 3.245±1.63 0.632±0.00 4.852±1.94 10.718±4.79 6.567±2.44
ENST00000418742 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.168±0.00 N/A N/A N/A
ENST00000457358 15.739±0.00 2.851±0.00 2.925±0.00 14.250±5.27 11.060±9.92 5.572±4.20 1.633±0.98 8.544±5.80 1.449±0.00 4.269±0.89 1.112±0.00 3.773±0.30 7.544±1.08 7.600±4.59
ENST00000490206 N/A N/A 4.565±0.00 N/A 7.617±0.00 N/A N/A 6.011±0.00 N/A 6.862±0.00 N/A 15.377±0.00 N/A 10.367±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 IEA:IBA GTPase activity
GO:0004871 IEA:IBA signal transducer activity
GO:0005515 IPI protein binding
GO:0005525 IEA:ISS GTP binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005765 IDA lysosomal membrane
GO:0005813 IDA centrosome
GO:0005834 IBA heterotrimeric G-protein complex
GO:0005886 IDA plasma membrane
GO:0006184 IEA GTP catabolic process
GO:0007049 IEA cell cycle
GO:0007165 IEA signal transduction
GO:0007186 IEA:ISS G-protein coupled receptor signaling pathway
GO:0007188 IEA:IBA adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007193 TAS adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007596 TAS blood coagulation
GO:0019001 IEA guanyl nucleotide binding
GO:0030168 TAS platelet activation
GO:0030496 IDA midbody
GO:0031683 IEA:IBA G-protein beta/gamma-subunit complex binding
GO:0031821 IBA G-protein coupled serotonin receptor binding
GO:0043434 ISS response to peptide hormone
GO:0046872 IEA metal ion binding
GO:0051301 IMP cell division
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030644 gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 protein_coding Danio_rerio
ENSMUSG00000057614 Gnai1 guanine nucleotide binding protein (G protein), alpha inhibiting 1 protein_coding Mus_musculus

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