C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: steroid 5 alpha-reductase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000128039 SRD5A3 9606 + 4:55346109-55373096 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264228 SRD5A3-001 55346109-55373096 protein_coding
  ENST00000505210 SRD5A3-002 55346412-55370310 protein_coding
  ENST00000514398 SRD5A3-003 55359000-55369975 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264228ENST00000505210
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264228 2.315±0.00 0.781±0.00 0.310±0.00 1.520±0.24 1.375±0.00 0.385±0.24 0.526±0.39 0.621±0.46 0.435±0.21 0.524±0.00 0.857±0.00 0.996±0.29 1.585±0.15 1.849±0.00
ENST00000505210 13.847±0.00 5.416±0.00 0.963±0.00 4.555±0.12 3.945±2.87 5.640±0.00 1.923±1.35 3.493±1.99 2.797±2.09 5.445±0.00 2.898±2.10 3.098±0.85 7.449±1.40 8.366±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00025J CIL_00025J_0001 CGP 4:55078477-55373096
CIL_00025I CIL_00025I_0001 CGP 4:55346109-55453397

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003865 IDA 3-oxo-5-alpha-steroid 4-dehydrogenase activity
GO:0005737 IEA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006488 IMP dolichol-linked oligosaccharide biosynthetic process
GO:0006489 TAS dolichyl diphosphate biosynthetic process
GO:0006629 IEA lipid metabolic process
GO:0006702 TAS androgen biosynthetic process
GO:0008202 TAS steroid metabolic process
GO:0016021 IEA integral component of membrane
GO:0016095 IDA polyprenol catabolic process
GO:0016627 IEA oxidoreductase activity, acting on the CH-CH group of donors
GO:0016628 IDA oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
GO:0018279 TAS protein N-linked glycosylation via asparagine
GO:0019348 IDA dolichol metabolic process
GO:0043687 TAS post-translational protein modification
GO:0044267 TAS cellular protein metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0047751 IEA cholestenone 5-alpha-reductase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043307 srd5a3 steroid 5 alpha-reductase 3 protein_coding Danio_rerio
ENSMUSG00000029233 Srd5a3 steroid 5 alpha-reductase 3 protein_coding Mus_musculus

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