C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: melanin-concentrating hormone receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000128285 MCHR1 9606 + 22:40678750-40682814 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000249016 MCHR1-001 40678750-40682814 protein_coding
  ENST00000381433 MCHR1-003 40679273-40682083 protein_coding
  ENST00000465662 MCHR1-004 40680107-40681412 processed_transcript
  ENST00000498400 MCHR1-002 40679273-40682083 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000249016ENST00000381433ENST00000465662ENST00000498400
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000249016 0.027±0.00 N/A 0.640±0.00 N/A N/A 0.039±0.00 N/A 0.330±0.00 0.060±0.00 0.524±0.47 0.046±0.02 0.106±0.00
ENST00000381433 0.047±0.00 0.310±0.00 0.920±0.00 N/A 0.246±0.00 N/A 0.364±0.00 N/A N/A 3.042±0.00 0.156±0.02 N/A
ENST00000465662 N/A N/A N/A 0.090±0.00 N/A N/A N/A N/A 0.423±0.00 0.357±0.12 0.136±0.00 N/A
ENST00000498400 N/A N/A N/A N/A N/A N/A 0.131±0.00 N/A N/A 0.557±0.00 0.091±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005W2 CIL_0005W2_0001 CGP 22:40410281-40682814
CIL_0005WB CIL_0005WB_0001 CGP 22:40678750-40819399

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004930 TAS:IEA G-protein coupled receptor activity
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006091 TAS generation of precursor metabolites and energy
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007193 TAS adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007218 IEA neuropeptide signaling pathway
GO:0007631 TAS feeding behavior
GO:0008022 IEA protein C-terminus binding
GO:0008188 TAS neuropeptide receptor activity
GO:0016021 IEA integral component of membrane
GO:0030273 IEA melanin-concentrating hormone receptor activity
GO:0031513 ISS nonmotile primary cilium
GO:0042562 IEA hormone binding
GO:0051928 IEA positive regulation of calcium ion transport
GO:0060170 IEA ciliary membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022525 mchr1b melanin-concentrating hormone receptor 1b protein_coding Danio_rerio
ENSDARG00000037048 mchr1a melanin-concentrating hormone receptor 1a protein_coding Danio_rerio
ENSMUSG00000050164 Mchr1 melanin-concentrating hormone receptor 1 protein_coding Mus_musculus

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