C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho GTPase activating protein 22
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000128805 ARHGAP22 9606 - 10:48446034-48656265 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000249601 ARHGAP22-001 48446034-48605093 protein_coding
  ENST00000374170 ARHGAP22-006 48446036-48524236 protein_coding
  ENST00000374172 ARHGAP22-005 48446036-48556678 protein_coding
  ENST00000417247 ARHGAP22-003 48446037-48493649 protein_coding
  ENST00000417912 ARHGAP22-002 48446340-48604952 protein_coding
  ENST00000435790 ARHGAP22-004 48446242-48652616 protein_coding
  ENST00000460425 ARHGAP22-008 48446558-48656265 nonsense_mediated_decay
  ENST00000464445 ARHGAP22-012 48582721-48652321 retained_intron
  ENST00000471013 ARHGAP22-009 48453357-48605088 processed_transcript
  ENST00000477708 ARHGAP22-007 48446036-48451627 protein_coding
  ENST00000489984 ARHGAP22-014 48454157-48466696 processed_transcript
  ENST00000491108 ARHGAP22-010 48574702-48604955 processed_transcript
  ENST00000493012 ARHGAP22-011 48532484-48583125 processed_transcript
  ENST00000511570 ARHGAP22-013 48575322-48583047 processed_transcript
  ENST00000515523 ARHGAP22-015 48453301-48479206 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000249601ENST00000374170ENST00000374172ENST00000417247ENST00000417912ENST00000460425ENST00000464445ENST00000477708ENST00000489984ENST00000491108ENST00000493012ENST00000511570
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000249601 N/A N/A N/A 0.986±0.48 N/A N/A N/A N/A N/A 0.285±0.00 N/A 2.224±0.00 0.540±0.00 N/A
ENST00000374170 N/A 0.862±0.00 N/A N/A N/A 0.412±0.00 N/A N/A 0.150±0.03 N/A N/A 2.846±0.00 0.606±0.00 0.987±0.00
ENST00000374172 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.956±0.00 N/A N/A
ENST00000417247 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.464±0.00 N/A 4.912±0.00 N/A N/A
ENST00000417912 N/A N/A N/A N/A 0.415±0.00 N/A 0.130±0.00 0.177±0.00 0.427±0.00 N/A N/A N/A N/A N/A
ENST00000460425 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.148±0.00 N/A 0.287±0.00 N/A N/A
ENST00000464445 N/A N/A N/A N/A N/A 1.417±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000477708 0.132±0.00 N/A N/A 2.117±0.00 0.603±0.00 N/A 0.452±0.33 0.213±0.00 N/A N/A 0.329±0.08 1.690±1.06 0.516±0.00 1.314±0.11
ENST00000489984 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.271±0.00 N/A N/A N/A
ENST00000491108 N/A N/A N/A 2.117±0.00 N/A 0.234±0.00 N/A N/A N/A N/A 0.893±0.00 N/A N/A N/A
ENST00000493012 0.304±0.00 0.943±0.00 0.166±0.00 1.907±0.00 0.854±0.00 0.305±0.00 0.571±0.33 0.799±0.00 0.385±0.03 0.333±0.00 0.447±0.00 1.644±1.33 N/A 3.074±2.02
ENST00000511570 N/A N/A N/A N/A N/A N/A N/A N/A 1.014±0.00 N/A N/A 0.860±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0005096 IEA GTPase activator activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0005925 IDA focal adhesion
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007165 IEA signal transduction
GO:0007264 TAS small GTPase mediated signal transduction
GO:0030154 IEA cell differentiation
GO:0043547 IEA positive regulation of GTPase activity
GO:0051056 TAS regulation of small GTPase mediated signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021255 arhgap22 Rho GTPase activating protein 22 protein_coding Danio_rerio
ENSDARG00000076434 ARHGAP22 (2 of 2) Rho GTPase activating protein 22 protein_coding Danio_rerio
ENSMUSG00000063506 Arhgap22 Rho GTPase activating protein 22 protein_coding Mus_musculus

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