C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adenylate cyclase 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000129467 ADCY4 9606 - 14:24318349-24335093 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000310677 ADCY4-001 24318349-24335071 protein_coding
  ENST00000418030 ADCY4-006 24318392-24334747 protein_coding
  ENST00000545213 ADCY4-008 24318365-24330608 retained_intron
  ENST00000554068 ADCY4-002 24318364-24335071 protein_coding
  ENST00000554577 ADCY4-007 24318364-24332484 retained_intron
  ENST00000554674 ADCY4-010 24330582-24332571 retained_intron
  ENST00000554781 ADCY4-005 24318392-24334747 nonsense_mediated_decay
  ENST00000554936 ADCY4-013 24322396-24323563 retained_intron
  ENST00000554959 ADCY4-012 24325407-24326515 retained_intron
  ENST00000555684 ADCY4-009 24318364-24319209 retained_intron
  ENST00000556932 ADCY4-011 24325824-24329468 protein_coding
  ENST00000557056 ADCY4-003 24318349-24335071 nonsense_mediated_decay
  ENST00000557099 ADCY4-004 24332238-24335093 retained_intron
  ENST00000558125 ADCY4-018 24332708-24335071 processed_transcript
  ENST00000558563 ADCY4-017 24332659-24335071 processed_transcript
  ENST00000559167 ADCY4-019 24332537-24335071 protein_coding
  ENST00000560635 ADCY4-015 24319306-24322363 retained_intron
  ENST00000561138 ADCY4-016 24332802-24335071 protein_coding
  ENST00000561200 ADCY4-014 24318925-24319779 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000310677ENST00000418030ENST00000545213ENST00000554068ENST00000554577ENST00000554674ENST00000554781ENST00000561200
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000310677 N/A N/A N/A N/A 3.441±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000418030 6.678±0.00 N/A N/A 1.920±0.00 N/A N/A N/A 0.546±0.14 N/A 0.627±0.28 4.566±0.00 11.401±1.36 N/A
ENST00000545213 N/A N/A 0.272±0.02 N/A N/A N/A N/A 0.314±0.00 N/A N/A N/A 2.407±0.00 0.724±0.00
ENST00000554068 9.046±0.00 9.102±0.00 0.409±0.31 5.662±0.00 N/A 1.858±0.00 2.749±0.00 N/A 5.543±0.00 N/A 2.203±0.00 6.933±0.33 2.397±0.00
ENST00000554577 N/A 2.423±0.00 0.155±0.00 N/A 0.281±0.00 N/A N/A N/A 0.633±0.00 N/A 1.183±0.00 N/A N/A
ENST00000554674 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.795±0.00 N/A N/A
ENST00000554781 6.332±0.00 N/A N/A 5.983±0.00 N/A 2.306±0.00 2.825±0.00 N/A 3.407±0.00 N/A 1.678±0.00 8.028±0.00 1.259±0.00
ENST00000561200 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.598±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004O4 CIL_0004O4_0001 CGP 14:24311450-24335093

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004016 ISS:IEA adenylate cyclase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005622 IEA intracellular
GO:0005737 IDA cytoplasm
GO:0005886 TAS plasma membrane
GO:0006112 TAS energy reserve metabolic process
GO:0006171 ISS cAMP biosynthetic process
GO:0006833 TAS water transport
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007188 ISS adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007189 TAS adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007193 TAS adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007268 TAS synaptic transmission
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009190 IEA cyclic nucleotide biosynthetic process
GO:0016020 ISS membrane
GO:0016021 IEA integral component of membrane
GO:0016849 IEA phosphorus-oxygen lyase activity
GO:0030425 IEA dendrite
GO:0034199 TAS activation of protein kinase A activity
GO:0035556 IEA intracellular signal transduction
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0046872 IEA metal ion binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0055085 TAS transmembrane transport
GO:0071377 TAS cellular response to glucagon stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000022220 Adcy4 adenylate cyclase 4 protein_coding Mus_musculus

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