C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dedicator of cytokinesis 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130158 DOCK6 9606 - 19:11199295-11262481 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000294618 DOCK6-001 11199295-11262452 protein_coding
  ENST00000585609 DOCK6-003 11247258-11262481 retained_intron
  ENST00000585904 DOCK6-012 11229001-11235754 protein_coding
  ENST00000586482 DOCK6-011 11252404-11253667 retained_intron
  ENST00000586702 DOCK6-009 11199295-11203313 processed_transcript
  ENST00000587572 DOCK6-010 11252882-11254048 retained_intron
  ENST00000587656 DOCK6-006 11199497-11236497 protein_coding
  ENST00000587734 DOCK6-018 11199303-11201963 protein_coding
  ENST00000588429 DOCK6-016 11215611-11217296 retained_intron
  ENST00000588666 DOCK6-017 11202082-11208944 protein_coding
  ENST00000590452 DOCK6-013 11228840-11229332 retained_intron
  ENST00000590680 DOCK6-005 11227337-11238290 protein_coding
  ENST00000591750 DOCK6-004 11235899-11238921 retained_intron
  ENST00000592403 DOCK6-015 11216676-11217268 retained_intron
  ENST00000592463 DOCK6-007 11206181-11208758 processed_transcript
  ENST00000592550 DOCK6-014 11221986-11222324 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000294618ENST00000586702ENST00000587656ENST00000588429ENST00000591750
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000294618 6.236±0.00 8.841±0.00 1.217±0.00 0.915±0.68 4.542±2.38 3.452±0.00 3.019±0.00 2.774±0.00 0.506±0.00 14.299±0.00 0.656±0.00 5.536±3.79 4.660±1.96 2.352±0.55
ENST00000586702 N/A N/A N/A N/A N/A 5.688±0.00 N/A N/A N/A 27.689±0.00 N/A 9.343±0.00 N/A 3.380±0.00
ENST00000587656 8.081±0.00 9.997±0.00 N/A 0.738±0.61 9.134±7.91 2.968±1.55 1.871±0.98 2.462±1.63 2.928±2.17 16.363±0.00 0.904±0.00 5.679±3.19 3.697±1.23 2.663±0.68
ENST00000588429 N/A N/A N/A 1.103±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000591750 N/A N/A N/A N/A N/A N/A N/A N/A 0.843±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001EZ CIL_0001EZ_0002 CGP 19:11164267-11262481
CIL_0003Q6 CIL_0003Q6_0001 CGP 19:11199295-11262481

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005829 TAS cytosol
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007596 TAS blood coagulation
GO:0043547 IEA positive regulation of GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035706 DOCK6 dedicator of cytokinesis 6 protein_coding Danio_rerio
ENSMUSG00000032198 Dock6 dedicator of cytokinesis 6 protein_coding Mus_musculus

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