C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: troponin I type 2 (skeletal, fast)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130598 TNNI2 9606 + 11:1838989-1841680 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000252898 TNNI2-201 1839697-1841680 protein_coding
  ENST00000381905 TNNI2-003 1840194-1841678 protein_coding
  ENST00000381906 TNNI2-001 1839481-1841678 protein_coding
  ENST00000381911 TNNI2-002 1838989-1841678 protein_coding
  ENST00000468473 TNNI2-004 1840218-1840735 retained_intron
  ENST00000617947 TNNI2-202 1839673-1841677 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000252898ENST00000381905ENST00000381906ENST00000381911
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000252898 N/A 2.212±0.00 N/A 0.098±0.00 162.578±0.00 0.438±0.07 0.081±0.00 0.177±0.11 0.169±0.00 5.561±0.00 293.580±0.00 0.668±0.00 3.579±1.24 6.242±0.00
ENST00000381905 0.837±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.320±0.00 N/A 0.629±0.00
ENST00000381906 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.522±0.00 N/A
ENST00000381911 N/A N/A 0.236±0.00 N/A 35.343±33.32 N/A N/A N/A 2.807±0.00 N/A 1101.441±361.08 0.686±0.19 3.205±1.20 3.168±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MR CIL_0008MR_0001 VISTA 11:1663842-2266142
CIL_0007RG CIL_0007RG_0001 VISTA 11:1668349-2271510
CIL_00097V CIL_00097V_0001 VISTA 11:1688064-2293510
CIL_00048J CIL_00048J_0001 CGP 11:1828307-1841680
CIL_0005ML CIL_0005ML_0002 CGP 11:1838989-1892267

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003009 IDA skeletal muscle contraction
GO:0003779 IDA actin binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005829 TAS cytosol
GO:0005861 IDA:IEA troponin complex
GO:0006937 IEA regulation of muscle contraction
GO:0030049 TAS muscle filament sliding
GO:0031014 IPI troponin T binding
GO:0045893 IDA positive regulation of transcription, DNA-templated

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005841 tnni2a.2 troponin I, skeletal, fast 2a, tandem duplicate 2 protein_coding Danio_rerio
ENSDARG00000013752 tnni2a.3 troponin I, skeletal, fast 2a, tandem duplicate 3 protein_coding Danio_rerio
ENSDARG00000029069 tnni2a.4 troponin I, skeletal, fast 2a, tandem duplicate 4 protein_coding Danio_rerio
ENSDARG00000029995 tnni2b.2 troponin I, skeletal, fast 2b, tandem duplicate 2 protein_coding Danio_rerio
ENSDARG00000035958 tnni2b.1 troponin I, skeletal, fast 2b, tandem duplicate 1 protein_coding Danio_rerio
ENSDARG00000045592 tnni2a.1 troponin I, skeletal, fast 2a, tandem duplicate 1 protein_coding Danio_rerio
ENSMUSG00000031097 Tnni2 troponin I, skeletal, fast 2 protein_coding Mus_musculus

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