C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 2, subfamily E, polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130649 CYP2E1 9606 + 10:133520406-133561220 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000252945 CYP2E1-201 133527363-133539116 protein_coding
  ENST00000368520 CYP2E1-004 133531576-133561220 retained_intron
  ENST00000418356 CYP2E1-008 133527497-133538811 protein_coding
  ENST00000421586 CYP2E1-007 133527497-133538811 protein_coding
  ENST00000463117 CYP2E1-001 133520406-133539122 protein_coding
  ENST00000469258 CYP2E1-005 133537500-133539118 processed_transcript
  ENST00000477500 CYP2E1-002 133527435-133532868 processed_transcript
  ENST00000480558 CYP2E1-003 133528079-133532164 processed_transcript
  ENST00000541080 CYP2E1-006 133527497-133538811 nonsense_mediated_decay
  ENST00000541261 CYP2E1-010 133525544-133528563 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungMuscleOvaryENST00000252945ENST00000368520ENST00000418356ENST00000421586ENST00000477500ENST00000480558ENST00000541261
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary
ENST00000252945 0.161±0.00 N/A N/A 2.679±0.00 1.774±0.00 0.072±0.00 407.940±407.60 1895.593±1895.38 0.520±0.00 N/A 0.844±0.36
ENST00000368520 N/A 0.066±0.00 N/A N/A N/A N/A 0.018±0.00 N/A 0.046±0.00 N/A N/A
ENST00000418356 N/A N/A 0.668±0.00 2.740±0.00 5.388±0.00 0.134±0.00 2138.680±0.00 N/A 1.056±0.00 0.469±0.00 0.201±0.00
ENST00000421586 N/A N/A N/A 1.122±0.00 N/A N/A N/A N/A N/A 0.454±0.00 N/A
ENST00000477500 N/A N/A N/A N/A N/A N/A N/A 0.556±0.00 N/A N/A 0.343±0.01
ENST00000480558 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.551±0.00
ENST00000541261 N/A N/A N/A N/A N/A N/A N/A 1.133±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00001G CIL_00001G_0001 CGP 10:133520406-133569835

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 IEA Golgi membrane
GO:0004497 IDA monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005739 IEA mitochondrion
GO:0005783 IEA endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006641 IEA triglyceride metabolic process
GO:0006805 TAS xenobiotic metabolic process
GO:0008202 IMP steroid metabolic process
GO:0010193 IEA response to ozone
GO:0010243 IEA response to organonitrogen compound
GO:0016098 IDA monoterpenoid metabolic process
GO:0016491 IDA oxidoreductase activity
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016709 TAS oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0016712 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0017144 IMP drug metabolic process
GO:0019825 TAS oxygen binding
GO:0019899 IPI enzyme binding
GO:0020037 IEA:IDA heme binding
GO:0031227 IEA intrinsic component of endoplasmic reticulum membrane
GO:0042493 IEA response to drug
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0045471 IEA response to ethanol
GO:0046483 IDA heterocycle metabolic process
GO:0055114 IDA:IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007173 cyp2y3 cytochrome P450, family 2, subfamily Y, polypeptide 3 protein_coding Danio_rerio
ENSDARG00000068493 si:zfos-411a11.2 si:zfos-411a11.2 protein_coding Danio_rerio
ENSMUSG00000025479 Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 protein_coding Mus_musculus

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