C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glucose-6-phosphatase, catalytic subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000131482 G6PC 9606 + 17:42900797-42913369 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000253801 G6PC-001 42900798-42913369 protein_coding
  ENST00000585489 G6PC-003 42900800-42911488 protein_coding
  ENST00000588481 G6PC-004 42900812-42904239 retained_intron
  ENST00000592383 G6PC-002 42900797-42911336 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000253801ENST00000585489ENST00000592383
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000253801 0.054±0.00 0.077±0.00 16.550±0.00 0.005±0.00 0.074±0.03 0.038±0.00 0.017±0.00 22.419±16.66 40.943±40.89 0.038±0.00 0.021±0.00 N/A 0.015±0.00 0.061±0.06
ENST00000585489 N/A N/A N/A N/A N/A 0.225±0.00 N/A N/A N/A N/A N/A 0.051±0.00 N/A N/A
ENST00000592383 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.010±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00044T CIL_00044T_0001 CGP 17:42851184-42913369
CIL_000447 CIL_000447_0001 CGP 17:42900797-42980528

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004346 IDA:IEA glucose-6-phosphatase activity
GO:0005783 IEA endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005975 TAS carbohydrate metabolic process
GO:0005977 TAS glycogen metabolic process
GO:0005980 IEA glycogen catabolic process
GO:0006094 IEA gluconeogenesis
GO:0006641 IEA triglyceride metabolic process
GO:0006796 IEA phosphate-containing compound metabolic process
GO:0008152 IEA metabolic process
GO:0008202 IEA steroid metabolic process
GO:0008645 TAS hexose transport
GO:0010468 IEA regulation of gene expression
GO:0015758 TAS glucose transport
GO:0015760 IEA glucose-6-phosphate transport
GO:0016020 IEA membrane
GO:0016021 IDA integral component of membrane
GO:0016311 IEA dephosphorylation
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0030176 TAS integral component of endoplasmic reticulum membrane
GO:0032094 IEA response to food
GO:0035264 IEA multicellular organism growth
GO:0042301 IMP phosphate ion binding
GO:0042593 IMP glucose homeostasis
GO:0042632 IEA cholesterol homeostasis
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0046415 IEA urate metabolic process
GO:0046838 IEA phosphorylated carbohydrate dephosphorylation
GO:0051156 IEA glucose 6-phosphate metabolic process
GO:0055085 TAS transmembrane transport
GO:0055088 IEA lipid homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013721 g6pca.2 glucose-6-phosphatase a, catalytic, tandem duplicate 2 protein_coding Danio_rerio
ENSDARG00000014967 g6pcb glucose-6-phosphatase b, catalytic protein_coding Danio_rerio
ENSDARG00000031616 g6pca.1 glucose-6-phosphatase a, catalytic, tandem duplicate 1 protein_coding Danio_rerio
ENSMUSG00000078650 G6pc glucose-6-phosphatase, catalytic protein_coding Mus_musculus

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