C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: telomeric repeat binding factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000132604 TERF2 9606 - 16:69355561-69408571 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000254942 TERF2-001 69355561-69385988 protein_coding
  ENST00000564982 TERF2-009 69367081-69372355 nonsense_mediated_decay
  ENST00000566051 TERF2-008 69356334-69361471 protein_coding
  ENST00000566257 TERF2-013 69367049-69384747 protein_coding
  ENST00000566750 TERF2-006 69366935-69385570 protein_coding
  ENST00000567130 TERF2-010 69361352-69366984 retained_intron
  ENST00000567296 TERF2-002 69370211-69385988 protein_coding
  ENST00000567841 TERF2-003 69372269-69408571 protein_coding
  ENST00000569280 TERF2-005 69370534-69385733 nonsense_mediated_decay
  ENST00000569542 TERF2-012 69366947-69384650 protein_coding
  ENST00000569584 TERF2-011 69364967-69372282 protein_coding
  ENST00000569611 TERF2-004 69368508-69385599 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainColonMuscleOvaryPlacentaTestisENST00000254942
Transcript ID Brain Colon Muscle Ovary Placenta Testis
ENST00000254942 13.883±9.18 16.649±0.00 42.335±0.00 18.950±3.26 13.299±3.13 18.326±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004I8 CIL_0004I8_0001 CGP 16:69343248-69408571
CIL_0008KB CIL_0008KB_0001 VISTA 16:69347064-69947578
CIL_0007FT CIL_0007FT_0001 CGP 16:69355561-69466266

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000723 IMP:IEA telomere maintenance
GO:0000781 IDA:IEA chromosome, telomeric region
GO:0000783 IDA nuclear telomere cap complex
GO:0000784 IEA nuclear chromosome, telomeric region
GO:0001309 NAS age-dependent telomere shortening
GO:0001673 IEA male germ cell nucleus
GO:0001701 IEA in utero embryonic development
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003691 ISS double-stranded telomeric DNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0007004 IC telomere maintenance via telomerase
GO:0007049 IEA cell cycle
GO:0008022 IPI protein C-terminus binding
GO:0010834 IMP telomere maintenance via telomere shortening
GO:0016233 IMP telomere capping
GO:0030870 IDA Mre11 complex
GO:0031627 IDA telomeric loop formation
GO:0031848 IMP protection from non-homologous end joining at telomere
GO:0032205 IDA negative regulation of telomere maintenance
GO:0032206 IEA positive regulation of telomere maintenance
GO:0032214 NAS negative regulation of telomere maintenance via semi-conservative replication
GO:0042162 IEA:IDA telomeric DNA binding
GO:0042803 IEA:IPI protein homodimerization activity
GO:0070198 IMP protein localization to chromosome, telomeric region
GO:0090398 NAS cellular senescence

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039302 terfa telomeric repeat binding factor a protein_coding Danio_rerio
ENSMUSG00000031921 Terf2 telomeric repeat binding factor 2 protein_coding Mus_musculus

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