C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nestin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000132688 NES 9606 - 1:156668763-156677397 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000368223 NES-001 156668763-156677397 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000368223
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000368223 48.950±0.00 30.107±0.00 1.643±0.00 5.851±5.33 15.677±13.38 14.811±13.61 27.305±21.82 17.386±16.76 2.454±1.48 23.970±20.66 11.058±8.36 11.185±11.34 15.222±4.95 15.817±12.12

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008JO CIL_0008JO_0001 VISTA 1:156202708-156805613
CIL_000850 CIL_000850_0001 VISTA 1:156360457-156965492

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 IDA G2/M transition of mitotic cell cycle
GO:0003674 ND molecular_function
GO:0005198 IEA structural molecule activity
GO:0005622 IEA intracellular
GO:0005737 IDA cytoplasm
GO:0005882 NAS:IEA intermediate filament
GO:0007399 IEA nervous system development
GO:0007417 NAS central nervous system development
GO:0007420 ISS brain development
GO:0019215 ISS intermediate filament binding
GO:0030844 ISS positive regulation of intermediate filament depolymerization
GO:0031076 ISS embryonic camera-type eye development
GO:0032091 IDA negative regulation of protein binding
GO:0043086 IDA negative regulation of catalytic activity
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0045111 IDA intermediate filament cytoskeleton
GO:0048858 IEA cell projection morphogenesis
GO:0072089 IMP stem cell proliferation
GO:2000179 ISS positive regulation of neural precursor cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088805 nes nestin protein_coding Danio_rerio
ENSMUSG00000004891 Nes nestin protein_coding Mus_musculus

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