C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dimethylglycine dehydrogenase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000132837 DMGDH 9606 - 5:78997606-79236038 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000255189 DMGDH-001 78997606-79069649 protein_coding
  ENST00000517853 DMGDH-003 79021507-79069629 nonsense_mediated_decay
  ENST00000518477 DMGDH-002 79021506-79069629 nonsense_mediated_decay
  ENST00000518707 DMGDH-008 79120277-79235938 processed_transcript
  ENST00000520388 DMGDH-006 79055854-79236038 processed_transcript
  ENST00000520855 DMGDH-007 79222146-79236005 processed_transcript
  ENST00000521052 DMGDH-005 79042427-79069674 nonsense_mediated_decay
  ENST00000523201 DMGDH-010 79026436-79030608 processed_transcript
  ENST00000523732 DMGDH-004 79020672-79054240 protein_coding
  ENST00000524206 DMGDH-009 79051287-79069626 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000255189ENST00000517853ENST00000518477ENST00000518707ENST00000521052ENST00000523201ENST00000523732ENST00000524206
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000255189 0.266±0.00 N/A 14.071±0.00 N/A 3.021±0.00 N/A N/A 26.804±10.98 3.629±2.93 N/A N/A 0.182±0.13 0.051±0.02 0.270±0.04
ENST00000517853 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.415±0.00
ENST00000518477 0.291±0.00 N/A N/A 0.292±0.00 N/A N/A N/A N/A N/A N/A 0.538±0.00 N/A 0.078±0.00 N/A
ENST00000518707 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.826±0.00 N/A N/A
ENST00000521052 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.186±0.00 N/A
ENST00000523201 N/A N/A N/A 0.773±0.00 N/A N/A N/A N/A N/A N/A N/A 0.556±0.40 0.099±0.00 N/A
ENST00000523732 0.375±0.00 0.400±0.00 N/A 0.309±0.00 1.563±0.00 0.162±0.00 0.221±0.00 N/A 4.345±0.00 0.119±0.00 N/A 0.290±0.00 0.082±0.02 0.639±0.27
ENST00000524206 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.154±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004047 IEA aminomethyltransferase activity
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005759 NAS mitochondrial matrix
GO:0006544 IMP glycine metabolic process
GO:0006546 IEA glycine catabolic process
GO:0006579 IEA amino-acid betaine catabolic process
GO:0009055 NAS electron carrier activity
GO:0016491 IEA oxidoreductase activity
GO:0019695 NAS choline metabolic process
GO:0032259 IEA methylation
GO:0044822 IDA poly(A) RNA binding
GO:0047865 IMP dimethylglycine dehydrogenase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025703 dmgdh dimethylglycine dehydrogenase protein_coding Danio_rerio
ENSMUSG00000042102 Dmgdh dimethylglycine dehydrogenase precursor protein_coding Mus_musculus

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