C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphatidylethanolamine N-methyltransferase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000133027 PEMT 9606 - 17:17505563-17591708 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000255389 PEMT-001 17505563-17591700 protein_coding
  ENST00000395781 PEMT-012 17505565-17591708 protein_coding
  ENST00000395782 PEMT-003 17505563-17577465 protein_coding
  ENST00000395783 PEMT-002 17505563-17582431 protein_coding
  ENST00000421096 PEMT-010 17508784-17591650 processed_transcript
  ENST00000435340 PEMT-009 17505563-17591679 protein_coding
  ENST00000461404 PEMT-005 17512514-17591700 nonsense_mediated_decay
  ENST00000472446 PEMT-004 17509434-17591703 processed_transcript
  ENST00000477595 PEMT-011 17505566-17507056 processed_transcript
  ENST00000484838 PEMT-007 17505563-17518157 processed_transcript
  ENST00000490392 PEMT-006 17505563-17519080 processed_transcript
  ENST00000580147 PEMT-013 17505589-17591683 nonsense_mediated_decay
  ENST00000582268 PEMT-017 17505563-17506323 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000255389ENST00000395782ENST00000395783ENST00000421096ENST00000435340ENST00000461404ENST00000472446ENST00000484838ENST00000490392ENST00000580147ENST00000582268
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000255389 13.192±0.00 6.811±0.00 N/A 9.727±0.00 43.584±0.00 6.383±0.00 5.638±0.00 14.024±0.00 10.925±9.99 6.515±6.39 6.355±5.75 14.956±7.25 11.688±6.00 11.039±7.60
ENST00000395782 13.078±0.00 3.451±0.00 1.440±0.00 N/A N/A 5.032±0.00 0.660±0.00 N/A 8.281±0.00 0.560±0.00 1.853±0.00 0.550±0.00 7.823±1.35 23.415±19.80
ENST00000395783 N/A N/A N/A N/A N/A N/A N/A 20.941±0.00 41.677±0.00 N/A N/A N/A N/A N/A
ENST00000421096 N/A N/A N/A N/A N/A 0.544±0.00 N/A N/A N/A N/A N/A 11.600±0.00 N/A N/A
ENST00000435340 8.330±0.00 5.375±0.00 N/A N/A N/A N/A N/A N/A N/A 2.964±0.00 N/A N/A N/A 8.929±0.00
ENST00000461404 N/A N/A N/A N/A N/A N/A 1.882±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000472446 N/A N/A N/A N/A N/A 0.829±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000484838 N/A N/A N/A N/A N/A 0.513±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000490392 N/A N/A N/A 1.323±0.00 23.801±0.00 0.446±0.00 N/A N/A N/A N/A N/A 6.441±0.00 N/A 15.354±0.00
ENST00000580147 N/A N/A N/A 1.115±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000582268 N/A N/A N/A 4.176±0.00 N/A N/A N/A 10.211±0.00 N/A N/A N/A 0.347±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009A0 CIL_0009A0_0001 VISTA 17:17235872-17840873
CIL_0000NN CIL_0000NN_0001 CGP 17:17494437-17591708
CIL_0000NM CIL_0000NM_0001 CGP 17:17505563-17811453

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000773 IEA phosphatidyl-N-methylethanolamine N-methyltransferase activity
GO:0004608 IEA phosphatidylethanolamine N-methyltransferase activity
GO:0005739 IEA mitochondrion
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006629 TAS lipid metabolic process
GO:0006644 TAS:IEA phospholipid metabolic process
GO:0006656 IEA phosphatidylcholine biosynthetic process
GO:0008170 IEA N-methyltransferase activity
GO:0008283 TAS cell proliferation
GO:0016021 IEA integral component of membrane
GO:0032259 IEA methylation
GO:0044281 TAS small molecule metabolic process
GO:0046474 TAS glycerophospholipid biosynthetic process
GO:0080101 IEA phosphatidyl-N-dimethylethanolamine N-methyltransferase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040450 pemt phosphatidylethanolamine N-methyltransferase protein_coding Danio_rerio
ENSMUSG00000000301 Pemt phosphatidylethanolamine N-methyltransferase protein_coding Mus_musculus

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