C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: relaxin/insulin-like family peptide receptor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000133105 RXFP2 9606 + 13:31739542-31803388 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000298386 RXFP2-001 31739542-31803388 protein_coding
  ENST00000380314 RXFP2-201 31739542-31802872 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainHeartKidneyLungOvaryTestisENST00000298386ENST00000380314
Transcript ID Adrenal Brain Heart Kidney Lung Ovary Testis
ENST00000298386 0.019±0.00 N/A N/A N/A N/A 0.057±0.05 0.051±0.00
ENST00000380314 N/A 0.014±0.00 0.004±0.00 0.032±0.00 0.083±0.00 N/A 0.055±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000PD CIL_0000PD_0003 CGP 13:31199936-31803388
CIL_0000PC CIL_0000PC_0003 CGP 13:31739542-32299122

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001556 IEA oocyte maturation
GO:0004930 IEA G-protein coupled receptor activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007189 IEA adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007193 IEA adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0008285 IEA negative regulation of cell proliferation
GO:0008584 IEA male gonad development
GO:0016021 IEA integral component of membrane
GO:0016500 IEA protein-hormone receptor activity
GO:0017046 IEA peptide hormone binding
GO:0030819 IEA positive regulation of cAMP biosynthetic process
GO:0043066 IEA negative regulation of apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019660 rxfp2a relaxin/insulin-like family peptide receptor 2a protein_coding Danio_rerio
ENSDARG00000032820 rxfp2b relaxin/insulin-like family peptide receptor 2b protein_coding Danio_rerio
ENSMUSG00000053368 Rxfp2 relaxin/insulin-like family peptide receptor 2 protein_coding Mus_musculus

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