C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myosin, heavy chain 11, smooth muscle
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000133392 MYH11 9606 - 16:15703135-15857033 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000300036 MYH11-001 15703991-15857033 protein_coding
  ENST00000396324 MYH11-006 15703172-15857011 protein_coding
  ENST00000452625 MYH11-013 15703172-15857011 protein_coding
  ENST00000570785 MYH11-011 15749168-15783532 retained_intron
  ENST00000571275 MYH11-008 15712896-15725138 retained_intron
  ENST00000571505 MYH11-004 15785015-15857028 retained_intron
  ENST00000571910 MYH11-014 15775842-15779423 retained_intron
  ENST00000573908 MYH11-012 15703741-15711270 processed_transcript
  ENST00000574119 MYH11-015 15741553-15742191 retained_intron
  ENST00000576164 MYH11-009 15712890-15724328 retained_intron
  ENST00000576790 MYH11-003 15703787-15857033 protein_coding
  ENST00000611087 MYH11-201 15703135-15857030 protein_coding
  ENST00000616439 MYH11-202 15703135-15857030 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000300036ENST00000396324ENST00000452625ENST00000576790ENST00000616439
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000300036 N/A N/A 1.439±0.00 0.533±0.00 N/A 48.913±0.00 0.607±0.00 0.303±0.00 422.032±0.00 N/A 1.860±0.00 6.525±1.55 10.962±0.93 16.841±0.00
ENST00000396324 66.229±0.00 N/A N/A 5.497±0.00 25.745±7.25 N/A 3.930±3.22 25.415±0.00 N/A 86.284±0.00 15.913±0.00 139.053±0.00 35.178±23.47 33.246±0.00
ENST00000452625 N/A N/A N/A N/A N/A 659.686±0.00 4.195±0.00 0.561±0.00 53.122±51.63 N/A 31.201±0.00 5.664±0.00 N/A N/A
ENST00000576790 44.928±0.00 135.739±0.00 3.918±0.00 8.307±0.00 13.449±0.00 614.828±0.00 5.446±4.81 N/A 144.847±0.00 3.857±0.00 14.675±0.00 55.221±0.00 N/A N/A
ENST00000616439 N/A N/A N/A N/A 21.875±0.00 N/A 0.624±0.00 18.494±0.00 89.989±0.00 99.239±0.00 N/A 63.017±18.90 22.890±10.08 797.880±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006UO CIL_0006UO_0001 CGP 16:15594386-15726353
CIL_0006MU CIL_0006MU_0001 CGP 16:15643267-15857033
CIL_0002TD CIL_0002TD_0001 CGP 16:15703135-15888625

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001725 IEA stress fiber
GO:0003774 IEA motor activity
GO:0005515 IPI:IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0005859 IEA muscle myosin complex
GO:0006936 TAS muscle contraction
GO:0006939 ISS smooth muscle contraction
GO:0007411 TAS axon guidance
GO:0008152 IEA metabolic process
GO:0008307 IMP structural constituent of muscle
GO:0016020 IEA membrane
GO:0016192 IEA vesicle-mediated transport
GO:0016459 IEA myosin complex
GO:0030241 ISS skeletal muscle myosin thick filament assembly
GO:0030485 IEA smooth muscle contractile fiber
GO:0032982 IEA myosin filament
GO:0048251 IMP elastic fiber assembly
GO:0048739 IMP cardiac muscle fiber development
GO:0051015 IEA actin filament binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009782 myh11a myosin, heavy polypeptide 11, smooth muscle a protein_coding Danio_rerio
ENSMUSG00000018830 Myh11 myosin, heavy polypeptide 11, smooth muscle protein_coding Mus_musculus

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