C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134308 YWHAQ 9606 - 2:9583972-9631014 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000238081 YWHAQ-001 9583972-9631014 protein_coding
  ENST00000381844 YWHAQ-002 9583972-9630616 protein_coding
  ENST00000446619 YWHAQ-005 9588298-9630946 protein_coding
  ENST00000460093 YWHAQ-003 9628703-9630268 processed_transcript
  ENST00000474715 YWHAQ-004 9585081-9620701 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000238081ENST00000381844ENST00000446619ENST00000474715
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000238081 80.793±0.00 69.478±0.00 4.298±0.00 85.542±62.97 35.425±23.80 55.613±37.86 20.859±18.24 43.920±37.42 17.827±1.34 43.915±31.56 4.420±0.00 69.791±35.83 71.481±18.49 55.302±24.50
ENST00000381844 N/A N/A N/A 16.200±0.00 N/A N/A 11.374±7.10 N/A 21.261±0.00 N/A 10.662±0.00 29.192±18.85 21.199±0.00 37.429±8.38
ENST00000446619 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.767±0.00 N/A N/A N/A
ENST00000474715 N/A N/A N/A N/A 11.290±0.00 N/A N/A N/A N/A 9.162±0.00 N/A 35.299±0.00 70.531±0.00 66.181±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001MI CIL_0001MI_0001 CGP 2:9488486-9631014

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005925 IDA focal adhesion
GO:0006605 IEA protein targeting
GO:0006915 TAS apoptotic process
GO:0007264 IEA small GTPase mediated signal transduction
GO:0016020 IDA membrane
GO:0019904 IEA protein domain specific binding
GO:0021762 IEP substantia nigra development
GO:0030659 TAS cytoplasmic vesicle membrane
GO:0043234 IPI protein complex
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0047485 IPI protein N-terminus binding
GO:0061024 TAS membrane organization
GO:0070062 IDA extracellular vesicular exosome
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:1900740 TAS positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000023323 ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b protein_coding Danio_rerio
ENSDARG00000042539 ywhaqa tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a protein_coding Danio_rerio
ENSMUSG00000076432 Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide protein_coding Mus_musculus

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