C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: kinase D-interacting substrate, 220kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134313 KIDINS220 9606 - 2:8725278-8837630 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000256707 KIDINS220-001 8728857-8837625 protein_coding
  ENST00000319688 KIDINS220-005 8757194-8837600 protein_coding
  ENST00000436566 KIDINS220-008 8725278-8727217 processed_transcript
  ENST00000459813 KIDINS220-006 8746457-8770707 protein_coding
  ENST00000471275 KIDINS220-010 8800207-8806378 retained_intron
  ENST00000471685 KIDINS220-012 8733609-8737289 retained_intron
  ENST00000473731 KIDINS220-002 8728929-8837630 protein_coding
  ENST00000474782 KIDINS220-013 8789984-8794316 retained_intron
  ENST00000488729 KIDINS220-003 8730201-8837596 nonsense_mediated_decay
  ENST00000489024 KIDINS220-011 8731953-8837612 protein_coding
  ENST00000496383 KIDINS220-007 8725560-8802971 protein_coding
  ENST00000496725 KIDINS220-009 8826702-8837613 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000256707ENST00000319688ENST00000473731ENST00000489024ENST00000496383
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000256707 N/A N/A 6.635±0.00 5.713±0.00 6.800±0.00 N/A 3.652±0.48 N/A 13.384±0.00 N/A 5.676±3.99 3.696±0.00 N/A N/A
ENST00000319688 N/A N/A N/A N/A 3.963±0.00 N/A N/A N/A 7.600±0.00 N/A N/A N/A N/A N/A
ENST00000473731 7.933±0.00 3.515±0.00 N/A 13.625±0.00 5.006±0.00 7.105±0.00 N/A 6.238±0.00 1.555±0.00 5.141±0.00 N/A 5.541±2.91 4.418±0.00 5.315±1.29
ENST00000489024 N/A N/A N/A 11.108±0.00 N/A 2.449±0.00 3.732±0.00 2.168±0.00 N/A N/A 3.614±0.00 N/A N/A N/A
ENST00000496383 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.212±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099S CIL_00099S_0001 VISTA 2:8341264-8943461
CIL_0002BL CIL_0002BL_0002 CGP 2:8678845-8837630
CIL_0007AQ CIL_0007AQ_0002 CGP 2:8725278-9003813

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000186 TAS activation of MAPKK activity
GO:0001701 IEA in utero embryonic development
GO:0005515 IEA protein binding
GO:0005770 ISS late endosome
GO:0005829 TAS cytosol
GO:0010976 ISS positive regulation of neuron projection development
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0016482 ISS cytoplasmic transport
GO:0030165 ISS PDZ domain binding
GO:0038180 ISS nerve growth factor signaling pathway
GO:0043234 ISS protein complex
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048813 IEA dendrite morphogenesis
GO:1990090 ISS cellular response to nerve growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017338 kidins220b kinase D-interacting substrate of 220b protein_coding Danio_rerio
ENSDARG00000031240 kidins220a kinase D-interacting substrate of 220a protein_coding Danio_rerio
ENSMUSG00000036333 Kidins220 kinase D-interacting substrate 220 protein_coding Mus_musculus

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