C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lipin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134324 LPIN1 9606 + 2:11677595-11827409 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000256720 LPIN1-001 11746588-11827409 protein_coding
  ENST00000396097 LPIN1-201 11724334-11827405 protein_coding
  ENST00000396098 LPIN1-004 11724352-11783945 protein_coding
  ENST00000396099 LPIN1-003 11724352-11824863 nonsense_mediated_decay
  ENST00000404113 LPIN1-005 11777207-11826530 processed_transcript
  ENST00000423495 LPIN1-007 11746638-11765625 protein_coding
  ENST00000425416 LPIN1-202 11724334-11827405 protein_coding
  ENST00000441684 LPIN1-006 11746634-11767858 protein_coding
  ENST00000449576 LPIN1-019 11677595-11824887 protein_coding
  ENST00000454151 LPIN1-010 11787130-11804519 protein_coding
  ENST00000460096 LPIN1-016 11782364-11784313 retained_intron
  ENST00000464517 LPIN1-012 11724350-11746130 processed_transcript
  ENST00000464953 LPIN1-009 11787047-11792349 retained_intron
  ENST00000475286 LPIN1-008 11783869-11784849 processed_transcript
  ENST00000475922 LPIN1-002 11816153-11826513 retained_intron
  ENST00000480315 LPIN1-013 11724350-11746130 processed_transcript
  ENST00000487346 LPIN1-011 11804440-11805515 retained_intron
  ENST00000487576 LPIN1-018 11823080-11825070 processed_transcript
  ENST00000495907 LPIN1-014 11724349-11765599 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000256720ENST00000396098ENST00000396099ENST00000404113ENST00000449576ENST00000487576
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000256720 8.285±0.00 3.757±0.00 0.653±0.00 5.513±0.57 3.174±0.82 5.043±0.00 2.824±2.18 2.566±1.09 3.182±0.00 2.412±1.62 7.455±2.45 5.673±6.00 2.152±0.69 7.308±0.00
ENST00000396098 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 43.671±0.00
ENST00000396099 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.877±0.00
ENST00000404113 N/A N/A 0.521±0.00 N/A 2.083±0.00 0.733±0.00 0.933±0.00 N/A 2.055±0.00 1.098±0.00 N/A N/A N/A N/A
ENST00000449576 N/A N/A N/A N/A N/A 1.997±0.00 0.476±0.00 N/A N/A 1.245±0.00 6.222±0.00 1.053±0.00 N/A 16.409±7.93
ENST00000487576 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.524±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000266 IEA mitochondrial fission
GO:0001085 IEA RNA polymerase II transcription factor binding
GO:0003674 ND molecular_function
GO:0003713 IEA transcription coactivator activity
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005667 IEA transcription factor complex
GO:0005737 ISS cytoplasm
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006629 IEA lipid metabolic process
GO:0006642 ISS triglyceride mobilization
GO:0006644 TAS phospholipid metabolic process
GO:0006646 TAS phosphatidylethanolamine biosynthetic process
GO:0006656 TAS phosphatidylcholine biosynthetic process
GO:0008195 IEA phosphatidate phosphatase activity
GO:0009062 IEA:ISS fatty acid catabolic process
GO:0016311 IEA dephosphorylation
GO:0019432 IEA:TAS triglyceride biosynthetic process
GO:0031065 IEA positive regulation of histone deacetylation
GO:0031100 IEA organ regeneration
GO:0031529 IEA ruffle organization
GO:0031532 IEA actin cytoskeleton reorganization
GO:0031965 ISS nuclear membrane
GO:0032869 IEA cellular response to insulin stimulus
GO:0042826 IEA histone deacetylase binding
GO:0042975 IEA peroxisome proliferator activated receptor binding
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045598 IEA regulation of fat cell differentiation
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046474 TAS glycerophospholipid biosynthetic process
GO:2001141 IEA regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020239 lpin1 lipin 1 protein_coding Danio_rerio
ENSDARG00000076096 LPIN1 (2 of 2) lipin 1 protein_coding Danio_rerio
ENSMUSG00000020593 Lpin1 lipin 1 protein_coding Mus_musculus

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